IDF Releases New Position Statement on 1-hour OGTT for Diagnosis of Prediabetes and T2DM - Ft. Dr V Mohan - Video

Published On 2024-03-31T19:30:27+05:30 | Updated On 1 April 2024 5:58 PM IST

Overview

The International Diabetes Federation (IDF) released a Position Statement recommending use of 1-hour post-load plasma glucose (1-h PG) test as a more sensitive and practical method to screen for intermediate hyperglycaemia (IH), (earlier known as Pre-Diabetes) and type 2 diabetes(T2D) in people at risk.

The Statement was prepared by an international panel of 22 experts from 15 countries and presented recently at the 17th International Conference on Advanced Technologies & Treatments for Diabetes (ATTD) in Florence, Italy and was published online in Diabetes Research and Clinical Practice. Dr. V. Mohan, Chairman, Madras Diabetes Research Foundation and Dr. Mohan;s Diabetes Specialities Centre represented India on this panel.

The Statement recommends the use of 1-h PG with the validated cut points of 155 mg/dL (8.6 mmol/L) for IH and 209 mg/dL(11.6 mmol/L) for T2D. Intermediate Hyperglycaemia is a state between normal glucose regulation (NGR) and T2D. It includes impaired fasting glycaemia (IFG) and impaired glucose tolerance (IGT).

Many individuals with intermediate Hyperglycaemia as defined by current diagnostic criteria, will progress to T2D. Evidence shows that T2D can be prevented by lifestyle modification and/or medications in people with IGT diagnosed by 2-h PG during a 75-gram oral glucose tolerance test (OGTT). Unfortunately, many people with T2D and those with IGT remain undiagnosed if an OGTT is not employed. Given the continued rising prevalence of diabetes worldwide, a more sensitive and practical method is therefore needed to detect people with IH and T2D for early diagnosis and intervention.

Speaking to the Medical Dialogues team, one of the panel members from India, Dr. V. Mohan, Chairman, of Madras Diabetes Research Foundation, and Dr. Mohan`s Diabetes Specialities Centre gives his valuable insights and emphasizes on the following-

1. The latest International Diabetes Federation(IDF) Position Statement on the 1-hour post-load plasma glucose(PG) for the diagnosis of intermediate hyperglycemia and type 2 diabetes?

2. Why were the 2-hr PG levels selected instead of 1-hr PG? What was the evidence background?

3. What is the 1-h threshold level during the OGTT that identifies individuals at risk for T2DM?

4. Evidence stating that 1-h PG greater than 155 mg/dl is associated with CV risk and Target organ damage?

5. Since, India has a huge burden of Prediabetes and Diabetes as reported in the last version of the ICMR-INDIAB study, with this IDF position statement, what are the actions that clinicians can consider for diagnosis of intermediate hyperglycemia and type 2 diabetes?

6. Can 1-hr PG screening help in the early identification of Prediabetes?

Speakers

Dr. Nandita Mohan

Dr. Nandita Mohan is a practicing pediatric dentist with more than 5 years of clinical work experience. Along with this, she is equally interested in keeping herself up to date about the latest developments in the field of medicine and dentistry which is the driving force for her to be in association with Medical Dialogues. She also has her name attached with many publications; both national and international. She has pursued her BDS from Rajiv Gandhi University of Health Sciences, Bangalore and later went to enter her dream specialty (MDS) in the Department of Pedodontics and Preventive Dentistry from Pt. B.D. Sharma University of Health Sciences. Through all the years of experience, her core interest in learning something new has never stopped. She can be contacted at editorial@medicaldialogues.in. Contact no. 011-43720751

Dr V Mohan

Dr. Viswanathan Mohan, M.D., Ph.D., D.Sc., FRCP, FNA, FACE, FTWAS, MACP is an internationally acclaimed Diabetologist and Scientist. He is the President & Chief of Diabetes Research, Madras Diabetes Research Foundation. He is also the Chairman & Chief Diabetologist of Dr. Mohan’s Diabetes Specialities Centre, Chennai. In 2012, Dr. Mohan was awarded the Padma Shri, one of the highest civilian award of the Govt. of India. He is also a member of the advisory board of Medical Dialogues.