Metformin use lowers risk of neurodegenerative diseases in diabetes patients
A recent meta-analysis showed that metformin use, especially long-term use is tied to a lower risk of neurodegenerative disease (ND) in diabetes patients. However, the researchers add, "owing to a substantial heterogeneity among studies, there is a need for high-quality randomized controlled trials to confirm the finding."
There has always been a controversy on the association between metformin use and neurodegenerative disease onset. To clarify the same, Zubing Mei, Anorectal Disease Institute of Shuguang Hospital, Shanghai, China, and colleagues aimed to determine the relationship between metformin use and ND risk based on data from population-based cohort studies in a systematic review and meta-analysis published in the journal Diabetic Medicine.
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Dr. Nandita Mohan
BDS, MDS( Pedodontics and Preventive Dentistry)