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The DFEND( Vitamin D supplementation compared to placebo in people with first episode psychosis) Randomized Clinical Trial
Overview
Results from a recent study suggest that vitamin D does not improve 6-month mental or physical health outcomes in patients with early psychosis. However, the researchers suggest that public health strategies, while developing population-wide interventions, should consider the high prevalence of vitamin D deficiency and insufficiency in this study population. The study was published in the JAMA Network Open on December 28, 2021.
Patients with psychotic disorders are at an increased risk of vitamin D deficiency. This is evident during first-episode psychosis (FEP) and is related to unfavorable mental and physical health outcomes. Fiona Gaughran, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London, UK, and colleagues aimed to examine whether vitamin D supplementation contributes to improved clinical outcomes in FEP in the DFEND --a multisite, double-blind, placebo-controlled, parallel-group randomized clinical trial from the UK.
For more details, check out the full story on the link below:
Vitamin D Fails To Improve Mental Health In Early Psychosis: DFEND Trial
Speakers
Dr. Nandita Mohan
BDS, MDS( Pedodontics and Preventive Dentistry)