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Eating fat fast food can trigger pain even if in good health

Published On 2022-11-26T09:30:17+05:30  |  Updated On 26 Nov 2022 10:22 AM GMT
Eating fat fast food can trigger pain even if in good health
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Overview

Scientists have long agreed that nerve damage and pain observed in people with diabetes or obesity is related to their metabolic state. Researchers from the University of Texas-Dallas are now challenging this notion. Could chowing down on fattening food alone be the driving factor behind pain in some people?

The findings are published in the journal Scientific Reports.

It's all the more reason to avoid a high-fat diet, no matter how healthy you are in general. Eating fattening food may even exacerbate preexisting conditions or hinder injury recovery. For their study, Burton and his team compared the effects of different diets on two sets of mice over eight weeks. One received normal food, while the other was fed a high-fat diet that would not induce diabetes or obesity since both can result from disease state-related pain such as diabetic neuropathy. They compared obese, diabetic mice with these mice as well.

The researchers looked for saturated fats in the blood of the mice consuming a high fat diet, and found that palmitic acid, the most common form of saturated fat, binds to a certain nerve cell receptor that leads to inflammation and mimics nerve damage.

The researchers hence encourage health care professionals to consider the dangerous effects from eating fattening foods not only in patients with obesity or at higher risk for diabetes, but in anyone who might be experiencing pain.

Reference:

Tierney, J.A., Uong, C.D., Lenert, M.E. et al. High-fat diet causes mechanical allodynia in the absence of injury or diabetic pathology. Sci Rep 12, 14840 (2022). https://doi.org/10.1038/s41598-022-18281-x

Speakers

Dr. Nandita Mohan

BDS, MDS( Pedodontics and Preventive Dentistry)

Dr. Nandita Mohan is a practicing pediatric dentist with more than 5 years of clinical work experience. Along with this, she is equally interested in keeping herself up to date about the latest developments in the field of medicine and dentistry which is the driving force for her to be in association with Medical Dialogues. She also has her name attached with many publications; both national and international. She has pursued her BDS from Rajiv Gandhi University of Health Sciences, Bangalore and later went to enter her dream specialty (MDS) in the Department of Pedodontics and Preventive Dentistry from Pt. B.D. Sharma University of Health Sciences. Through all the years of experience, her core interest in learning something new has never stopped. She can be contacted at editorial@medicaldialogues.in. Contact no. 011-43720751
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