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Medical Therapy for Alcohol Use Disorder Likely To Reduce Alcohol Associated Liver Disease - Video

Published On 2022-05-25T18:15:13+05:30  |  Updated On 26 May 2022 5:50 PM IST
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Overview

A recent cohort study investigated patients with alcohol use disorder, those who received medical addiction therapy and found they had a significantly lower risk of developing alcohol-associated liver disease, whereas patients with cirrhosis who received medical addiction therapy had a significantly lower incidence of hepatic decompensation. Findings published in JAMA Open Network suggest an association between use of medical addiction therapy for alcohol use disorder and decreased incidence and progression of alcohol-associated liver disease.

Medical addiction therapy was defined as the documented use of disulfiram, acamprosate, naltrexone, gabapentin, topiramate, or baclofen. Patients were considered to be treated if they initiated medical addiction therapy before the relevant outcome.

Incidence of alcohol-associated liver disease was 0.37. This association was evident in naltrexone 0.67, gabapentin 0.36, topiramate 0.47, and baclofen 0.57. In addition, pharmacotherapy for alcohol use disorder was associated with lower incidence of hepatic decompensation in patients with cirrhosis, including naltrexone and gabapentin. This association persisted even when medical addiction therapy was initiated only after the diagnosis of cirrhosis.

Researchers concluded that results of this study showed that receipt of medical addiction therapy for alcohol use disorder was associated with reduced incidence and progression of alcohol-associated liver disease.

Speakers

Dr. Nandita Mohan

Dr. Nandita Mohan is a practicing pediatric dentist with more than 5 years of clinical work experience. Along with this, she is equally interested in keeping herself up to date about the latest developments in the field of medicine and dentistry which is the driving force for her to be in association with Medical Dialogues. She also has her name attached with many publications; both national and international. She has pursued her BDS from Rajiv Gandhi University of Health Sciences, Bangalore and later went to enter her dream specialty (MDS) in the Department of Pedodontics and Preventive Dentistry from Pt. B.D. Sharma University of Health Sciences. Through all the years of experience, her core interest in learning something new has never stopped. She can be contacted at editorial@medicaldialogues.in. Contact no. 011-43720751
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