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Amoxicillin linked to Fixed Drug Eruption, reveals IPC Drug Safety Alert
Overview
The Indian Pharmacopoeia Commission (IPC), through its recently issued drug safety alert for the month of October has revealed that penicillin-like antibiotics Amoxicillin is linked with Adverse Drug Reactions (ADRs) named Fixed Drug Eruption which is a distinctive type of cutaneous drug reaction.
This came after preliminary analysis of Adverse Drug Reactions (ADRs) from the Pharmacovigilance Programme of India (PvPI) database.
Amoxicillin is a penicillin derivative used for the treatment of infections caused by gram-positive bacteria, in particular streptococcal bacteria causing upper respiratory tract infections. Furthermore, Amoxicillin is indicated for the treatment of urinary tract infections, upper respiratory-tract infections, bronchitis, pneumonia, otitis media, dental abscess, osteomyelitis, Lyme diseases in children, endocarditis prophylaxis, post-splenectomy prophylaxis, gynaecological infections, gonorrhoea, helicobacter pylori eradication enteric fever.
For more details, check out the link given below:
Amoxicillin Linked To Fixed Drug Eruption: Indian Pharmacopoeia Commission Drug Safety Alert