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Medical Bulletin 18/March/2023

Published On 2023-03-18T15:41:32+05:30  |  Updated On 18 March 2023 10:11 AM GMT
Medical Bulletin 18/March/2023

Overview

Here are the top medical news for the day:


New gene-editing technique reverses vision loss

Researchers in China have successfully restored the vision of mice with retinitis pigmentosa, one of the major causes of blindness in humans. The study, that was published in the Journal of Experimental Medicine, uses a new, highly versatile form of CRISPR-based genome editing with the potential to correct a wide variety of disease-causing genetic mutations.

Retinitis pigmentosa can be caused by mutations in over 100 different genes and is estimated to impair the vision of 1 in 4,000 people. It begins with the dysfunction and death of dim light-sensing rod cells, before spreading to the cone cells required for color vision, eventually leading to severe, irreversible vision loss.

Reference:

New gene-editing technique reverses vision loss in mice; Journal of Experimental Medicine, DOI: 10.1084/jem.20220776


Few primary care physicians provide longer-acting birth control methods

Medicaid beneficiaries face barriers in accessing medical care - and that includes contraceptive care. A new study finds that despite birth control being an essential health service, all primary care physicians that see them may not be offering Medicaid patients some of the most effective, longer-acting birth control methods. While nearly half (48%) of primary care physicians who treat Medicaid patients provided prescription contraception like the birth control pill, only 10% provided longer-acting methods like IUDs and implants. This is in accordance to a new study published in JAMA Health Forum.

In this analysis, the researchers found that a physician’s characteristics - including their clinical specialty, age, gender and the Medicaid expansion status of their state - were associated with both providing any contraceptive care and with the number of beneficiaries provided contraceptive care.

Reference:

Few Medicaid-participating primary care physicians providing longer-acting birth control methods; JAMA Health Forum


Nervous system might play a key role in severe allergic shock

A key feature of the severe allergic reaction known as anaphylaxis is an abrupt drop in blood pressure and body temperature, causing people to faint and, if untreated, potentially die.

That response has long been attributed to a sudden dilation and leakage of blood vessels. But in a study using mice, Duke Health researchers have found that this response, especially body temperature drop, requires an additional mechanism – the nervous system.

Reference:

Key role identified for nervous system in severe allergic shock; Science Immunology

Speakers

Dr. Nandita Mohan

BDS, MDS( Pedodontics and Preventive Dentistry)

Dr. Nandita Mohan is a practicing pediatric dentist with more than 5 years of clinical work experience. Along with this, she is equally interested in keeping herself up to date about the latest developments in the field of medicine and dentistry which is the driving force for her to be in association with Medical Dialogues. She also has her name attached with many publications; both national and international. She has pursued her BDS from Rajiv Gandhi University of Health Sciences, Bangalore and later went to enter her dream specialty (MDS) in the Department of Pedodontics and Preventive Dentistry from Pt. B.D. Sharma University of Health Sciences. Through all the years of experience, her core interest in learning something new has never stopped. She can be contacted at editorial@medicaldialogues.in. Contact no. 011-43720751
Journal of Experimental Medicine vision loss blindness vision eye diseases mutation genetic disorders crisprs retinitis pigmentosa crispr gene editing JAMA Health Forum birth control pregnancy human reproduction birth control methods Science Immunology Nervous system allergies anaphylaxis 
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