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Coming wave of opioid overdoses - Video

Published On 2022-07-30T09:30:14+05:30  |  Updated On 30 July 2022 3:13 PM IST
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Overview

Over the past 21 years of opioid overdose deaths-from prescription drugs to heroin to synthetic and semisynthetic opioids such as fentanyl-geography has played a role in where opioid-involved overdose deaths have occurred, reports a new Northwestern Medicine study.

But the coming wave will not discriminate between rural and urban areas, the study findings suggest. Every type of county-from the most rural to the most urban-is predicted to see dramatic increases in deaths from opioid-involved overdoses, the study's author said.

The study examined geographic trends in opioid-involved overdose deaths between 1999 and 2020 to determine if geography played a role in the three waves and the theorized fourth wave of America's opioid crisis. The authors used data recorded in the Centers for Disease Control and Prevention's WONDER database for 3,147 counties and county equivalents categorized on a six-point urbanicity scale (most urban to most rural).

While some researchers have looked at an acceleration rate from one year to the next, the study authors said, to their knowledge, no one has examined acceleration rates of opioid-involved overdose death rates systematically by geography for every year.

The study authors examined toxicology reports and found people are using fentanyl (a synthetic opioid that is 50 to 100 times more potent than morphine) and carfentanil (a synthetic opioid approximately 100 times more potent than fentanyl) combined with methamphetamines and cocaine. The result is a powerful and lethal cocktail that can even evade help from overdose-reversing drugs like naloxone.

"The only path forward is to increase awareness to prevent opioid use disorders and to provide medication-assisted treatment that is culturally appropriate and non-stigmatizing in rural communities," the authors noted.

Ref:

Lori Post et. al,Geographic Trends in Opioid Overdoses in the U.S. From 1999 to 2020, JAMA Network Open, 28-Jul-2022, 10.1001/jamanetworkopen.2022.23631

Speakers

Isra Zaman

B.Sc Life Sciences, M.Sc Biotechnology, B.Ed

Isra Zaman is a Life Science graduate from Daulat Ram College, Delhi University, and a postgraduate in Biotechnology from Amity University. She has a flair for writing, and her roles at Medicaldialogues include that of a Sr. content writer and a medical correspondent. Her news pieces cover recent discoveries and updates from the health and medicine sector. She can be reached at editorial@medicaldialogues.in.

Dr. Kamal Kant Kohli

Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751
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