How alcohol consumption contributes to chronic pain - Video

Published On 2023-04-26T17:14:58+05:30 | Updated On 26 April 2023 5:14 PM IST

Overview

Chronic alcohol consumption may make people more sensitive to pain through two different molecular mechanisms-one driven by alcohol intake and one by alcohol withdrawal. That is one new conclusion by scientists at Scripps Research on the complex links between alcohol and pain.

The research, published in the British Journal of Pharmacology on April 12, 2023, also suggests potential new drug targets for treating alcohol-associated chronic pain and hypersensitivity.

“There is an urgent need to better understand the two-way street between chronic pain and alcohol dependence,” says senior author Marisa Roberto, PhD, the Schimmel Family Chair of Molecular Medicine, and a professor of neuroscience at Scripps Research. “Pain is both a widespread symptom in patients suffering from alcohol dependence, as well as a reason why people are driven to drink again.”

Reference:

Borgonetti, V., Roberts, A. J., Bajo, M., Galeotti, N., & Roberto, M. (2023). Chronic alcohol induced mechanical allodynia by promoting neuroinflammation: a mouse model of alcohol‐evoked neuropathic pain. British Journal of Pharmacology. https://doi.org/10.1111/bph.16091

Speakers

Isra Zaman

B.Sc Life Sciences, M.Sc Biotechnology, B.Ed

Isra Zaman is a Life Science graduate from Daulat Ram College, Delhi University, and a postgraduate in Biotechnology from Amity University. She has a flair for writing, and her roles at Medicaldialogues include that of a Sr. content writer and a medical correspondent. Her news pieces cover recent discoveries and updates from the health and medicine sector. She can be reached at editorial@medicaldialogues.in.