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Study finds marijuana users to be thrice more likely to develop peripheral artery disease - Video

Published On 2023-05-19T09:30:47+05:30  |  Updated On 19 May 2023 9:30 AM IST
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Overview

Marijuana use has increased in recent years with nearly 50 million people reporting using it at least once (CDC). While many studies have looked at the impact of marijuana use on health, little research has been done to study the effect of marijuana use on the vascular system. PAD, a condition in which narrowed arteries reduce blood flow to the arms or legs, impacts 6.5 million people in the U.S. and can lead to a loss of mobility, reduced quality of life, heart attack, stroke and death, if not treated early.

Findings from a study examining the relationship between marijuana use and peripheral artery disease (PAD) were presented today at the Society for Cardiovascular Angiography & Interventions (SCAI) 2023 Scientific Sessions. Results found marijuana users are at a significantly increased risk of developing PAD, compared to the general population.

Researchers used de-identified patient data from the National Inpatient Samples (NIS) from 2016-2019 who reported marijuana use and a diagnosis PAD. Patients were further stratified based on any percutaneous lower extremity vascular intervention. Data was analyzed using SPSS software in a binary logistic regression model, a p value <0.001 was considered statistically significant, and samples were standardized for comparison using predicted probabilities.

Of the 30 million patients identified, 623,768 were diagnosed as marijuana users. Patients had an average age of 37.4 years, equal distribution across genders, were more likely to be white and more likely to be elective admissions. Of these patients, 2,424 (0.38%) were also diagnosed with PAD. Marijuana users were at more than three times the risk of developing PAD (OR= 3.68, p<0.001) but had no statistically significant increased risk for mortality or requiring percutaneous intervention (p<0.001).

“With the increase in marijuana use in the U.S., our findings show that users should be aware of the symptoms of PAD such as leg pain while walking, slower or no hair growth and feelings of coldness in the leg,” said Hirva Vyas, DO, Hackensack University Medical Center, Hackensack, NJ and lead author of the study. “We know PAD is a progressive disease that can drastically impact quality of life, making ongoing monitoring of this patient population critical.”

Authors note that based on study results, vigilant monitoring for disease screening and progression should be initiated earlier in the outpatient setting in addition to cessation counseling.

Reference:

SOCIETY FOR CARDIOVASCULAR ANGIOGRAPHY AND INTERVENTIONS,MEETING SCAI Scientific Sessions,ORIGINAL SOURCE: https://scai.org/media-center/news-and-articles

Speakers

Isra Zaman

B.Sc Life Sciences, M.Sc Biotechnology, B.Ed

Isra Zaman is a Life Science graduate from Daulat Ram College, Delhi University, and a postgraduate in Biotechnology from Amity University. She has a flair for writing, and her roles at Medicaldialogues include that of a Sr. content writer and a medical correspondent. Her news pieces cover recent discoveries and updates from the health and medicine sector. She can be reached at editorial@medicaldialogues.in.

Dr. Kamal Kant Kohli

Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751
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