According to the study, in COVID-19 patients, elevated urinary NGAL (uNGAL) was associated with acute kidney injury (development), increased duration and severity of AKI, prolonged hospitalization, the degree of histopathological acute tubular injury, need for dialysis, and death. The findings of the study were presented at the American Society of Nephrology (ASN) Kidney Week 2021.
Kidney injury occurs commonly in COVID-19 patients, but serum creatinine (SCr) is not a sensitive or specific marker of kidney injury. Katherine Xu, Columbia University Irving Medical Center, New York, New York, United States, and colleagues hypothesized that measurement of molecular markers of tubular injury can diagnose COVID-19 associated kidney injury and predict a poor prognosis in a prospective cohort study.
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