Estrogen might be protective against brain shrinkage - Video

Estrogens reportedly is known to affect the development and aging of brain regions that are crucial to higher cognitive functions (like memory) and are implicated in neuropsychiatric disorders such as Alzheimer's disease.

A recent study has revealed an association between more estrogen exposure over the lifetime to greater brain volumes and fewer indicators of brain disease on brain scans in midlife. Reproductive history events signaling more estrogen exposure include longer reproductive span, pre-menopausal status, use of hormonal therapy (HT) and hormonal contraceptives (HC), and a higher number of children.

The study published in Neurology, the medical journal of the American Academy of Neurology on November 3, 2021 found that a number of ways a woman is exposed to estrogen—not having reached menopause, having more total reproductive years, having a higher number of children, using menopause hormone therapy or hormonal contraceptives—were associated with larger gray matter volumes in midlife.

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Is Estrogen Protective Against Risk Of Brain Shrinkage?