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Journal Club: Low-Dose Steroids for Management of Delayed Pericontusional Edema After Mild Traumatic Brain Injury - Video
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Overview
This research has been published in the Surgical Neurology International published by Scientific Scholar.
This study was a retrospective, single-center, 4-year study. The study analyzed patients who had received systemic corticosteroids for pericontusional delayed edema after traumatic brain injury. The time interval to steroid prescription, drug dosage, time to symptomatic improvement, and complications were analyzed. There were 19 males and eight females. Mean age was 42.1 years. Except for one, all were mild TBI categories. All patients had brain contusions on computed tomography. Dexamethasone was used in tapering doses over 5–10 days, starting with 12 mg/day. The mean interval to steroid prescription after the trauma was 5.9 days, and the mean and median duration was 7 days. All, except one, had symptomatic improvement. The mean time to complete improvement in symptoms was 2.8 days. There were no complications pertinent to steroid usage in any of our cases.
Therefore, it was concluded that this is the third clinical study to document the efficacy of systemic corticosteroids for delayed cerebral edema after traumatic brain injury. As steroids are excellent drugs for vasogenic edema, the timing and dosage of steroids are two important factors that will determine their efficacy in traumatic brain injury. The authors strongly feel that there needs to be more robust clinical trials with good patient numbers to confirm these findings.
Ref: Prasad G L, Pai A, Swamy PT. Short course of low-dose steroids for management of delayed pericontusional edema after mild traumatic brain injury – A retrospective study. 24-Jan-2025;16:23.
Speakers
Dr. Garima Soni
BDS, MDS(orthodontics)
Dr. Garima Soni holds a BDS (Bachelor of Dental Surgery) from Government Dental College, Raipur, Chhattisgarh, and an MDS (Master of Dental Surgery) specializing in Orthodontics and Dentofacial Orthopedics from Maitri College of Dentistry and Research Centre. At medical dialogues she focuses on dental news and dental and medical fact checks against medical/dental mis/disinformation
Dr. Nandita Mohan
BDS, MDS( Pedodontics and Preventive Dentistry)
Dr. Nandita Mohan is a practicing pediatric dentist with more than 5 years of clinical work experience. Along with this, she is equally interested in keeping herself up to date about the latest developments in the field of medicine and dentistry which is the driving force for her to be in association with Medical Dialogues. She also has her name attached with many publications; both national and international. She has pursued her BDS from Rajiv Gandhi University of Health Sciences, Bangalore and later went to enter her dream specialty (MDS) in the Department of Pedodontics and Preventive Dentistry from Pt. B.D. Sharma University of Health Sciences. Through all the years of experience, her core interest in learning something new has never stopped. She can be contacted at editorial@medicaldialogues.in. Contact no. 011-43720751