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Journal Club-Are maternal psychological stress and insulin resistance during pregnancy interrelated? - Video

Published On 2023-11-07T09:30:05+05:30  |  Updated On 8 Nov 2023 3:30 PM IST
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Overview

Various physiological mechanisms counteract insulin resistance (IR) during normal pregnancy. Psychological stress is a known, independent risk factor for developing insulin resistance. Pregnancy-specific psychological stress may cause insulin resistance and increase the risk of overt diabetes. Hence, the present study that I am talking about today aimed to evaluate maternal psychological stress using multiple stress markers and also understand their association with changes in insulin resistance during pregnancy and postpartum.

The researchers measured the anthropometric measurements such as height, weight and skinfold thickness using standard techniques. The stress markers were assessed among fifty healthy pregnant women during pregnancy and postpartum using perceived stress scales, a physiological marker of stress and biochemical stress markers. Insulin resistance was estimated using homeostasis model assessment-estimated IR (HOMA-IR).

The results published in Indian Journal of Physiology and Pharmacology (Scientific Scholar) showed that the psychological stress scores and saliva cortisol were significantly higher during pregnancy than postpartum. As assessed by HOMA-IR values, IR was significantly higher during the prenatal period than postpartum. There was a significant positive correlation between prenatal psychological stress scores, HRV parameters and postnatal IR.

Therefore, the researchers concluded that Pregnancy is associated with higher psychological stress levels and IR than postpartum and that the maternal cardiac autonomic marker could predict postnatal IR among healthy pregnant women.

Reference: Kishan A, Shetty PK, Moodithaya SS. Evaluation of an association between maternal prenatal psychological stress and insulin resistance during pregnancy and postpartum. Indian J Physiol Pharmacol 2023;67:105-12.

Speakers

Dr. Nandita Mohan

Dr. Nandita Mohan is a practicing pediatric dentist with more than 5 years of clinical work experience. Along with this, she is equally interested in keeping herself up to date about the latest developments in the field of medicine and dentistry which is the driving force for her to be in association with Medical Dialogues. She also has her name attached with many publications; both national and international. She has pursued her BDS from Rajiv Gandhi University of Health Sciences, Bangalore and later went to enter her dream specialty (MDS) in the Department of Pedodontics and Preventive Dentistry from Pt. B.D. Sharma University of Health Sciences. Through all the years of experience, her core interest in learning something new has never stopped. She can be contacted at editorial@medicaldialogues.in. Contact no. 011-43720751

Dr. Kamal Kant Kohli

Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751
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