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False-Positive Mammograms May Deter Women from Future Screenings: Research Finds
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Overview
A major, new study led by the UC Davis Comprehensive Cancer Center has found that women who received a false-positive result that required additional imaging or biopsy were less likely to return for that follow-up screening.
The research was published in the Annals of Internal Medicine and analyzed data on more than 3.5 million screening mammograms nationwide performed between 2005-2017 on over 1 million patients aged 40 to 73.
The study found that 77% of women with a negative result from a mammogram returned for subsequent screening. But this percentage dropped to 61% after a false-positive finding requiring another mammogram in six months to confirm the results and 67% if a biopsy was recommended. The impact was even more pronounced for women who received false-positive results on two consecutive mammograms recommending short-interval follow-up -- only 56% returned their next screening mammogram.
The high rate of women who don't return for future screening is concerning to the research team.
The research also showed that Asian and Hispanic/Latinx women were the least likely to return for future screening mammograms after a false positive result, which may contribute to existing health disparities.
False-positive results are common, especially among younger women. They occur in 10-12% of mammograms in women 40-49 years of age. After 10 years of annual screenings, 50-60% of women can expect at least one false-positive, and 7-12% at least one false-positive with a biopsy recommendation.
It is important for women to understand that about 10% of the time, additional imaging is necessary to get a better look at a finding on a screening mammogram.
Reference: Miglioretti, D. L., Abraham, L., Sprague, B. L., Lee, C. I., Bissell, M. C. S., Ho, T.-Q. H., Bowles, E. J. A., Henderson, L. M., Hubbard, R. A., Tosteson, A. N. A., & Kerlikowske, K. (2024). Association between false-positive results and return to screening mammography in the Breast Cancer Surveillance Consortium cohort. Annals of Internal Medicine. https://doi.org/10.7326/M24-0
Speakers
Dr. Garima Soni
BDS, MDS(orthodontics)
Dr. Garima Soni holds a BDS (Bachelor of Dental Surgery) from Government Dental College, Raipur, Chhattisgarh, and an MDS (Master of Dental Surgery) specializing in Orthodontics and Dentofacial Orthopedics from Maitri College of Dentistry and Research Centre. With 2 years of dedicated clinical experience, she brings a blend of academic excellence and practical expertise to the field of dentistry, ensuring high-quality care and innovative solutions for patients.