PPIs use to cause fracture risk in rheumatoid arthritis - Video

Rheumatoid arthritis is an auto immune disorder that causes pain, swelling, stiffness and loss of function in your joints. It can affect any joint but is common in the wrist and fingers. This greatly affects ones quality of life.

Concomitant use of PPIs and oral glucocorticoids increases risk of osteoporotic fractures by 1.6-fold in rheumatoid arthritis (RA) patients (aged 50 years and above), finds a recent study. The results of the study, published in the BMJ journal Annals of the Rheumatic Diseases, suggests that fracture risk assessment should be considered when a RA patient is prescribed both oral GCs and PPIs.

Rheumatoid arthritis patients commonly use proton pump inhibitors (PPIs) and oral glucocorticoids (GCs) both of which are associated with osteoporotic fractures. Shahab Abtahi, Maastricht University Medical Centre, Maastricht, The Netherlands, and colleagues investigated the association between concomitant use of oral GCs and PPIs and osteoporotic fractures risk among RA patients.

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PPI, oral glucocorticoids use linked to fracture risk in rheumatoid arthritis patients: BMJ