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Gut bacteria from toddler may predict whether they will be overweight at 5 years old: study - Video

Published On 2023-05-22T09:15:58+05:30  |  Updated On 22 May 2023 9:15 AM IST
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Overview

The make-up and volume of gut bacteria in toddlers at 3.5 years old is predictive of body mass index (BMI) at age 5, irrespective of whether they are born prematurely or not, according to new research, being presented at this year’s European Congress on Obesity (ECO) in Dublin, Ireland (17-20 May).

To find out more, the study investigated how the gut microbiota of children at 3.5 years from two French nationwide birth cohorts was associated with their BMI at 5 years old and changes in their BMI between 2 and 5 years old, after adjusting for confounding factors including child age and sex, gestational age, delivery mode, ever breastfed, maternal preconception BMI, and country of birth.

Overall, 143 preterm infants were included from EPIPAGE2—a national study conducted in all maternity and neonatal units in France in 2011—and 369 full-term infants from ELFE—a national study tracking the lives of 18,000 children born in metropolitan France in 2011.

Stool samples were collected at 3.5 years. Genetic microbiota profiling revealed a positive association between BMI z-score at 5 years and the ratio of gut bacteria Firmicutes to Bacteroidetes that are directly involved with obesity—the more Bacteroidetes, the leaner individuals tend to be.

Greater abundances of three categories of bacteria—Eubacterium hallii group, Fusicatenibacter, and Eubacterium ventriosum group—were identified as a risk factor for a higher BMI z-score; and greater numbers of three types of bacteria—Eggerthella, Colidextribacter, and Ruminococcaceae CAG-352—were associated with a lower BMI z-score.

Reference :EUROPEAN ASSOCIATION FOR THE STUDY OF OBESITY,MEETING European Congress on Obesity (ECO2023)

Speakers

Isra Zaman

B.Sc Life Sciences, M.Sc Biotechnology, B.Ed

Isra Zaman is a Life Science graduate from Daulat Ram College, Delhi University, and a postgraduate in Biotechnology from Amity University. She has a flair for writing, and her roles at Medicaldialogues include that of a Sr. content writer and a medical correspondent. Her news pieces cover recent discoveries and updates from the health and medicine sector. She can be reached at editorial@medicaldialogues.in.

Dr. Kamal Kant Kohli

Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751
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