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Common origin behind major childhood allergies - Video

Published On 2023-12-29T09:30:02+05:30  |  Updated On 29 Dec 2023 9:30 AM IST
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Overview

Several major childhood allergies may all stem from the community of bacteria living in our gut, according to a new study led by researchers at the University of British Columbia and BC Children's Hospital.

The research, published in Nature Communications, identifies gut microbiome features and early life influences that are associated with children developing any of four common allergies -- eczema, asthma, food allergy and/or hay fever.

The findings could lead to methods of predicting whether a child will develop allergies, and ways to prevent them from developing at all.

"We're seeing more and more children and families seeking help at the emergency department due to allergies," said Dr. Stuart Turvey, professor in the department of pediatrics at UBC and an investigator at BC Children's Hospital Research Institute, and co-senior author on the study.

"Hundreds of millions of children worldwide suffer from allergies, including one in three children in Canada, and it's important to understand why this is happening and how it can be prevented."

For the study, researchers examined clinical assessments from 1,115 children who were tracked from birth to age five.

Roughly half of the children (523) had no evidence of allergies at any time, while more than half (592) were diagnosed with one or more allergic disorders by an expert physician.

The researchers evaluated the children's microbiomes from stool samples collected at clinical visits at three months and one year of age.

Reference: Courtney Hoskinson, Darlene L. Y. Dai, Kate L. Del Bel, Allan B. Becker, Theo J. Moraes, Piushkumar J. Mandhane, B. Brett Finlay, Elinor Simons, Anita L. Kozyrskyj, Meghan B. Azad, Padmaja Subbarao, Charisse Petersen, Stuart E. Turvey. Delayed gut microbiota maturation in the first year of life is a hallmark of pediatric allergic disease. Nature Communications, 2023; 14 (1) DOI: 10.1038/s41467-023-40336-4

Speakers

Anshika Mishra

Anshika Mishra is a dedicated scholar pursuing a Masters in Biotechnology, driven by a profound passion for exploring the intersection of science and healthcare. Having embarked on this academic journey with a passion to make meaningful contributions to the medical field, Anshika joined Medical Dialogues in 2023 to further delve into the realms of healthcare journalism.

Dr. Kamal Kant Kohli

Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751
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