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Common origin behind major childhood allergies discovered - Video

Published On 2023-08-30T09:15:42+05:30  |  Updated On 30 Aug 2023 9:15 AM IST
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Overview

Several major childhood allergies may all stem from the community of bacteria living in our gut, according to a new study led by researchers at the University of British Columbia and BC Children’s Hospital. The research, published in Nature Communications, identifies gut microbiome features and early life influences that are associated with children developing any of four common allergies — eczema, asthma, food allergy, and/or hay fever. The findings could lead to methods of predicting whether a child will develop allergies and ways to prevent them from developing at all.

For the study, researchers examined clinical assessments from 1,115 children who were tracked from birth to age five. The researchers evaluated the children’s microbiomes from stool samples collected at clinical visits at three months and one year of age.

The stool samples revealed a bacterial signature that was associated with the children developing any of the four allergies by five years of age. The bacterial signature is a hallmark of dysbiosis, or an imbalanced gut microbiota, that likely resulted in a compromised intestinal lining and an elevated inflammatory response within the gut.

Many factors can shape the infant's gut microbiota, including diet, how we are born, where we live, and our exposure to antibiotics. For example, antibiotics may wipe out sensitive bacteria, while breastfeeding tends to replenish and provide necessary food for bacteria in the infant's gut. The researchers examined how these types of influences affected the balance of gut microbiota and the development of allergies.

Reference: Dr. Stuart Turvey et al, Nature Communications, DOI 10.1038/s41467-023-40336-4

Speakers

Isra Zaman

B.Sc Life Sciences, M.Sc Biotechnology, B.Ed

Isra Zaman is a Life Science graduate from Daulat Ram College, Delhi University, and a postgraduate in Biotechnology from Amity University. She has a flair for writing, and her roles at Medicaldialogues include that of a Sr. content writer and a medical correspondent. Her news pieces cover recent discoveries and updates from the health and medicine sector. She can be reached at editorial@medicaldialogues.in.

Dr. Kamal Kant Kohli

Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751
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