DM Medical Genetics: Admissions, Medical Colleges, Fees, Eligibility Criteria details
DM Medical Genetics or Doctorate of Medicine in Medical Genetics also known as DM in Medical Genetics is a super specialty level course for doctors in India that is done by them after completion of their postgraduate medical degree course. The duration of this super specialty course is 3 years, and it focuses on the diagnosis, treatment and management of hereditary/genetic disorders.
The course is a full-time course pursued at various recognized medical colleges across the country. Some of the top medical colleges offering this course include- Sanjay Gandhi Postgraduate Institute of Medical Sciences- Lucknow, All India Institute of Medical Sciences- Rishikesh, Kasturba Medical College- Manipal, and more.
Admission to this course is done through the NEET-SS Entrance exam conducted by the National Board of Examinations, followed by counselling based on the scores of the exam that is conducted by DGHS/MCC/State Authorities.
The fee for pursuing DM (Medical Genetics) varies from college to college and may range from Rs. 25000 to Rs. 15,00,000 per year.
After completion of their respective course, doctors can either join the job market or can pursue certificate courses and Fellowship programmes recognised by NMC and NBE. Candidates can take reputed jobs at positions as Senior residents, Consultants etc. with an approximate salary range of Rs 5 Lakh- Rs 20 Lakh per year.
What is DM in Medical Genetics?
Doctorate of Medicine in Medical Genetics, also known as DM (Medical Genetics) or DM in (Medical Genetics) is a three-year super specialty programme that candidates can pursue after completing postgraduate degree.
Medical Genetics is the branch of medical science that deals with the diagnosis, treatment and management of hereditary/genetic disorders.
National Medical Commission (NMC), the apex medical regulator, has released guidelines for a Competency-Based Postgraduate Training Programme for DM in Medical Genetics.
The Competency-Based Postgraduate Training Programme governs the education and training of DMs in Medical Genetics.
The postgraduate students must gain ample of knowledge and experience in the diagnosis, treatment of patients with acute, serious, and life-threatening medical and surgical diseases.
The PG education intends to create specialists who can contribute to high-quality health care and advances in science through research and training.
The required training done by a postgraduate specialist in the field of Medical Genetics would help the specialist to recognize the health needs of the community. The student should be competent to handle medical problems effectively and should be aware of the recent advances in their speciality.
The candidate is also expected to know the principles of research methodology and modes of the consulting library. The candidate should regularly attend conferences, workshops and CMEs to upgrade her/ his knowledge.
Course Highlights
Here are some of the course highlights of DM in Medical Genetics
| Name of Course | DM in Medical Genetics |
| Level | Doctorate |
| Duration of Course | Three years |
| Course Mode | Full Time |
| Minimum Academic Requirement | Postgraduate medical degree obtained from any college/university recognized by the MCI (Now NMC)/NBE |
| Admission Process / Entrance Process / Entrance Modalities | Entrance Exam (NEET-SS) INI CET for various AIIMS, PGIMER Chandigarh, JIPMER Puducherry, NIMHANS Bengaluru Counselling by DGHS/MCC/State Authorities |
| Course Fees | Rs. 25000 to Rs. 15,00,000 per year |
| Average Salary | Rs 5 Lakh- Rs 20 Lakh per year |
Eligibility Criteria
The eligibility criteria for DM in Medical Genetics are defined as the set of rules or minimum prerequisites that aspirants must meet in order to be eligible for admission, which include:
- Candidates must be in possession of a postgraduate medical Degree (MD/MS/DNB) from any college/university recognized by the MCI (Now NMC)/NBE.
- The candidate must have obtained permanent registration of any State Medical Council to be eligible for admission.
- The medical college's recognition cut-off dates for the Postgraduate Degree courses shall be as prescribed by the Medical Council of India (now NMC).
Admission Process
- The admission process contains a few steps to be followed in order by the candidates for admission to DM in Medical Genetics. Candidates can view the complete admission process for DM in Medical Genetics mentioned below:
- The NEET-SS or National Eligibility Entrance Test for Super specialty courses is a national-level master's level examination conducted by the NBE for admission to DM/MCh/DrNB Courses.
- Qualifying Criteria-Candidates placed at the 50th percentile or above shall be declared as qualified in the NEET-SS in their respective specialty.
- The following Medical institutions are not covered under centralized admissions for DM/MCh courses through NEET-SS:
- AIIMS, New Delhi and other AIIMS
- 2.PGIMER, Chandigarh
- 3.JIPMER, Puducherry
- 4.NIMHANS, Bengaluru
- Candidates from all eligible feeder specialty subjects shall be required to appear in the question paper of respective group, if they are willing to opt for a superspecialty course in any of the super specialty courses covered in that group.
- A candidate can opt for appearing in the question papers of as many groups for which his/her Postgraduate specialty qualification is an eligible feeder qualification.
- By appearing in the question paper of a group and on qualifying the examination, a candidate shall be eligible to exercise his/her choices in the counseling only for those superspecialty subjects covered in said group for which his/ her broad specialty is an eligible feeder qualification.
Fees Structure
The fee structure for DM in Medical Genetics varies from college to college. The fee is generally less for Government Institutes and more for private institutes. The average fee structure for DM in Medical Genetics is around Rs. 25000 to Rs. 15,00,000 per year.
Colleges offering DM in Medical Genetics
There are various medical colleges across India that offer courses for pursuing DM in (Medical Genetics).
As per National Medical Commission (NMC) website, the following medical colleges are offering DM in (Medical Genetics) courses for the academic year 2022-23.
| Sl.No. | Course Name | Select a State | Name and Address of Medical College / Medical Institution | Annual Intake (Seats) |
| 1 | DM - Medical Genetics | Uttar Pradesh | Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow | 2 |
| 2 | DM - Medical Genetics | Uttarakhand | All India Institute of Medical Sciences, Rishikesh | 4 |
| 3 | DM - Medical Genetics | Karnataka | Kasturba Medical College, Manipal | 2 |
| 4 | DM - Medical Genetics | Chandigarh | Postgraduate Institute of Medical Education & Research, Chandigarh |
Syllabus
A DM in Medical Genetics is a three years specialization course that provides training in the stream of Medical Genetics.
The course content for DM in Medical Genetics is given in the Competency-Based Postgraduate Training Programme released by National Medical Commission, which can be assessed through the link mentioned below:
Course contents:
A. Cognitive domain
History of Medical Genetics
Foundations of Medical Genetics Before 1956
Growth and Development of Medical Genetics: 1956 to the Present
The Future
Genetics in Medicine
The Principles of Disease, Defining Disease, Prevention and Treatment
Nature and Frequency of Genetic Disease
Frequency of Genetic Disease
Single-Gene Disorders
Multifactorial Disorders
Somatic Cell Genetic Disorders
Genomics and Proteomics
Genes and Human Disease
Genomics
Mapping the Human Genome
Sequencing the Human Genome
Current Approaches to Sequence Human Genome
Cloning Human Disease Genes
Sequence-Based Methods for Detecting Chromosomal Abnormalities
Proteomics
Genome and Gene Structure
Double Helix Structure, DNA Replication, Transcription, and Meiotic Recombination
Organization of Genomic DNA
Gene Structure and the Molecular Pathway of Gene Expression
Epigenetics
Epigenetic Mechanisms: Chromatin, DNA Methylation and Long Noncoding RNAs
Epigenetic Reprogramming
Epigenetic Regulation of X Inactivation
Genomic Imprinting
Genetic Disorders Due to Genes Affecting Chromatin Structure
Methods for Studying Epigenetic Marks
Cancer Epigenetics
Environmental Influences on Epigenetic Traits
Abnormalities in Epigenetic Programming Linked to Infertility and ART
In Utero Epigenetic Programming of Adult Traits and Disease
Genetic–Epigenetic Interactions
Human Gene Mutation in Inherited Disease: Molecular Mechanisms and Clinical Consequences
Molecular Mechanisms of Mutation Causing Human Inherited Disease
Disease-Causing Mutations, Consequences of Mutations
General Principles of Genotype–Phenotype Correlations
Genes in Families
Pedigree Construction
Unifactorial Inheritance/Single-Gene Disorders
Dominance and Recessiveness
Autosomal-Dominant Inheritance
Autosomal Recessive Inheritance
Sex-Linked Inheritance
X-Linked Recessive Inheritance
X-Linked Dominant Inheritance
Y-Linked (Holandric) Inheritance
Partial Sex Linkage
Analysis of Genetic Linkage
Linkage Analysis: Basic Concepts
Extending Parametric Linkage Analysis
Linkage Analysis for Complex and Quantitative Traits
Chromosomal Basis of Inheritance
Chromosome Structure, Chromosomes in Cell Division
Methods for Studying Human Chromosomes
Functional Organization of Chromosomes
Sex Chromosomes and Sex Determination
Uniparental Disomy and Imprinting
Chromosome Abnormalities
Mitochondrial Genetics
Mitochondrial Biology and Genetics
Mitochondrial Etiology for Diseases and cancer
Therapeutic Approaches to Mitochondrial Disease
Multifactorial Inheritance and Complex Diseases
Determining the Genetic Component of a Trait
The International HapMap Project
Genome-Wide Association Studies
Association Methods/Statistical Analysis
Analysis of Rare Variants Using New Technologies
Integration of Genetic, Genomic, and Functional Data for Multifactorial Diseases
Population Genetics
Hardy–Weinberg Law, Factors that affect Hardy–Weinberg Equilibrium
Applications in Population Genetics
Pathogenetics of Disease
The Scope of Abnormal Phenotypes: Disease and Malformation
Multivariate Normal Distributions and the Threshold Model
Pathogenetics of Refined Traits
Molecular Pathogenetics
Human Developmental Genetics
The Concept of Developmental Fields and Field Defects
Cellular Signaling in Development
Steps and Concepts in Embryonic Development
Regulation of Gene Expression in Development
Organogenesis
Twins and Twinning
Determining Zygosity
Incidence of Twins, Vanishing Twin, Structural Defects in Twins
Twins in Genetic Studies
Dizygotic Twins, Monozygotic Twins
The Molecular Biology of Cancer
Genetic Basis of Cancer
Viral Oncogenes
Oncogenic Alleles in Human Cancers
Tumor Suppressor Genes
The Role of DNA Damage Repair Genes in Inherited Cancer Syndromes
The Biological Basis of Aging: Implications for Medical Genetics
Progeroid Syndromes of Humans
Human Allelic Variants Homologous to Pro-Longevity Genes
Pharmacogenetics and Pharmacogenomics
Classical Genetics and Pharmacogenetics
Ethnic Differences in Gene–Drug Interactions
Pharmacogenomics
Genetic Evaluation for Common Diseases of Adulthood
The Process of Genetic Evaluation for Common Diseases
Integrating Genetic Information into Routine Clinical Practice
Genetic Counseling and Clinical Risk Assessment
Process of Genetic Counseling
Adult-Onset Disorders
Genetic Risk Assessment and Calculation in the Clinical Setting
Cytogenetic Analysis
Milestones in Human Cytogenetics
The Indications for Cytogenetic Analysis
Tissue Samples and Cell Culture, Chromosome Banding
The Normal Human Karyotype
Chromosome Abnormalities
In situ Hybridization
Diagnostic Molecular Genetics
Indications for Molecular Genetic Testing
Technical Approaches to Molecular Genetic Testing
Molecular Genetic Diagnosis of Diseases
Mitochondrial DNA Disorders
Quality Assurance, and Regulatory Issues
Internet Resources for Molecular Genetic Testing
Heterozygote Testing and Carrier Screening
Carrier Screening in Clinical Practice
Carrier Screening in Individuals of Defined Subpopulation Groups
Therapeutic Implications for Heterozygotes
Methods and Tissues used in Carrier Identification
Problems in Heterozygote Detection
Sensitivity and Specificity, Cost and Feasibility
Age for Carrier Testing
Prenatal Screening for Neural Tube Defects and Aneuploidy
Techniques for Prenatal Diagnosis
Amniocentesis, Chorionic Villus Sampling, Fetal Blood Sampling, Fetal Tissue
Sampling, Celomocentesis
Embryoscopy
Polar Body Biopsy, Preimplantation Genetic Diagnosis
Ultrasonography
Fetal Cells and Fetal DNA in Maternal Blood
Neonatal Screening
Historical Aspects
Components of Screening Programs
Potential Problems in Newborn Screening
Disorders and Conditions Detected by Newborn Blood Screening
Other Newborn Screening and Issues and Concerns in Screening
Therapies for Lysosomal Storage Diseases
ERT for Lysosomal Storage Diseases
Substrate Reduction Therapy
Pharmacologic Chaperone Therapy
Gene Therapy: From Theoretical Potential to Clinical Implementation
Genes as Medicines -The Origins of Gene Therapy
The Basic Science: Gene Transfer
Developing Cell-Type-Specific and Regulatable Gene Delivery Vectors
The Clinical Science: Toward Gene Therapy of Human Disease
Ethical and Social Issues in Clinical Genetics
Genetic Counseling, Testing and Screening
Goals and Outcomes of Genetic Services
Non-directiveness in Genetic Counseling
Diagnostic Genetic Testing, Predictive Genetic Testing
Confidentiality
Genetic Testing in Childhood, Population Genetic Screening, Newborn Screening,
Antenatal Screening, Carrier Screening
Genetics, Geneticization and Society
Reproductive Technologies and Cloning: "Reprogenetics"
Legal Issues in Medical Genetics
Genetic Malpractice
Genetic Counseling, Abortion, Adoption, Surrogacy, Embryo cryopreservation
Newborn Screening
Prenatal and Carrier Screening
Genetic Discrimination
Regulation of Genetic Diagnostic Tests
Direct to Consumer Genetic Testing
Regulation of Human Genetic Research
Regulation of Research with Stem Cells Derived from Human Embryos
Genetics of Male & Female Infertility
The Hypothalamic – Pituitary - Gonadal Axis
Hypogonadism: Hypogonadotropic & Hypergonadotropic Hypogonadism
Eugonadal Infertility
Chromosome Anomalies and Gene defects
Fetal Loss
Early Pregnancy Loss, Late Pregnancy Loss
Evaluation and Management of Recurrent Abortion
Clinical Approach to the Dysmorphic Child
Prenatal versus Postnatal Onset of Developmental Problems
Clinical Teratology
Recognized Teratogenic Exposures
Paternal Exposures and Maternal Exposures
Neurodevelopmental Disabilities: Global Developmental Delay, Intellectual Disability, and
Autism
Abnormal Body Size and Proportion
Pathologic Short Stature
Pathologic Overgrowth
Susceptibility and Response to Infection
Genome-Wide Association Studies and Human Infection
Cell Surface Proteins, Intracellular Proteins, Extracellular Proteins
Transplantation Genetics
The Physiologic Function of MHC Molecules
The Structure of Human Histocompatibility Molecules
Minor Histocompatibility Systems
Serologic, Cellular and Molecular Methods for HLA Typing
Clinical Significance of HLA Molecular Typing
Genetics of Xenotransplantation
Stem Cells and Transplantation
The Genetics of Disorders Affecting the Premature Newborn
Respiratory Distress Syndrome, Bronchopulmonary Dysplasia
Patent Ductus Arteriosus
Intraventricular Hemorrhage
Retinopathy of Prematurity
Necrotizing Enterocolitis
Disorders of DNA Repair and Metabolism
Disorders of Nucleotide Excision Repair: Xeroderma Pigmentosum and Cockayne
Syndrome
Disorders of Base Excision Repair: MUTYH and Colon Cancer Risk
Disorders of Mismatch Repair: Lynch Syndrome and Turcot Syndrome
Disorders Associated with Double Strand Break Recognition and Repair: AtaxiaTelangiectasia and Related Conditions
Crosslink Repair and Homologous Recombination Defects: Breast–Ovarian Cancer and
Fanconi Anemia
Disorders Associated with Recq Helicase Deficiency: Bloom, Werner, and Rothmund–
Thomson Syndromes
Gene - Environment Interactions: Gorlin - Goltz Syndrome
Autosomal Abnormalities
Genetic Counseling in the Trisomies
Down Syndrome (Trisomy 21), Trisomy 18, Trisomy 13
Translocations
Uniparental Disomy
Deletion, Duplication
Sex-Chromosome Abnormalities
Turner Syndrome, Klinefelter Syndrome, 47,XXX Syndrome, 47,XYY Karyotype
Sex Chromosome Mosaicism
Sex Chromosome Tetrasomy and Pentasomy (Polysomy)
Structural Abnormalities of the Y Chromosome
Prenatal Diagnosis of Sex Chromosome Abnormalities
Cardio-vascular system: Congenital Heart Defects and Inherited Cardiomyopathies
Specific Syndromes with Congenital Heart Defect
Chromosomal Disorders
Microdeletions/Microduplication Syndromes
Single-Gene Disorders
Holt–Oram syndrome
CHARGE Syndrome
Maternal Diabetes, Drug Ingestion
Folic Acid Supplementation
Risks for Sibs and Offspring of Children with Isolated Heart Defects
Hypertrophic, Dilated and Atypical Cardiomyopathy
Hereditary Hemorrhagic Telangiectasia (Osler–Weber–Rendu Syndrome)
Hereditary Disorders of the Lymphatic System and Venous System (varicose vein)
Capillary Malformation/Arteriovenous Malformation (Capillary Malformation, Sturge–
Weber Syndrome, Capillary Malformation–arteriovenous Malformation, Cerebral
Cavernous Malformation)
The Genetics of Cardiac Electrophysiology in Humans
Genetics of Blood Pressure Regulation
Preeclampsia
Common Genetic Determinants of Coagulation and Fibrinolysis (Genetic Variants
Influencing Components of the Coagulation Cascade, Genetic Variants Influencing
Natural Anticoagulants, Genetic Variants Influencing Components of the Fibrinolytic
Cascade, Genetic Variants Influencing Platelet Function, Genome-Wide Association
Analysis for Thrombosis)
Genetics of Atherosclerotic Cardiovascular Disease (Genetic Studies of CHD, Candidate
Gene Studies in Humans, Genome Wide Association Studies, GWAS Findings for CVD
Risk Factors, Genetic Risk Scores and Prediction Algorithms for Personalized Medicine)
Respiratory tract disorders
Cystic Fibrosis
Genetic Underpinnings of Asthma and Related Traits
Disorders of ciliary function
Hereditary Pulmonary Emphysema
Interstitial and Restrictive Pulmonary Disorders
Congenital Anomalies of the Kidney and Urinary Tract
Cystic Diseases of the Kidney
Nephrotic Disorders
Renal Tubular Disorders
Cancer of the Kidney and Urogenital Tract
Gastrointestinal Tract and Hepatobiliary Duct System
Inflammatory Bowel Disease
Bile Pigment Metabolism and its Disorders including cholestasis
Cancer of the Colon and Gastrointestinal Tract
Blood
Hemoglobinopathies and Thalassemia
Other Hereditary Red Blood Cell Disorders
Hemophilia and Other Disorders of Hemostasis
Rhesus and Other Fetomaternal Incompatibilities
Disorders of bone marrow aplasia and dyserythropoesis
Immunologic Disorders: Autoimmunity: Genetics and Immunologic Mechanisms
Immunodeficiency Disorders
Inherited Complement Deficiencies
Disorders of Leukocyte Function
Genetic Basis of Autoimmune Thyroid Disease
Endocrine
Abnormalities of growth hormone- pituitary axis
Monogenic diabetes mellitus
Susceptibility to type I and type II diabetes
Genetic Basis of Thyroid Carcinoma
Familial Hypocalciuric Hypercalcemia
CASR Mutations in Familial Hypocalciuric Hypercalcemia and Neonatal Severe
Hyperparathyroidism
Neonatal Hyperparathyroidism
Multiple Endocrine Neoplasia
Familial Isolated Hypoparathyroidism
NHERF1 Mutations and Renal Responsiveness to Parathyroid Hormone
Adrenal Gland
Congenital Adrenal Hyperplasia (21, 11β, 3β, 17α-Hydroxylase Deficiency, 17,20-Lyase
Deficiency, Congenital Lipoid Adrenal Hyperplasia, etc): Prenatal Diagnosis and
Treatment
Congenital adrenal hypoplasia
Reproductive system
Disorders of the Gonads, Genital Tract, and Genitalia
Disorders of Sexual Development and differentiation
Hereditary Cancers
Familial Breast Cancers (BRCA1, BRCA2)
Familial Breast or Ovarian Cancer
Familial Ovarian Cancer
Familial Endometrial Cancer
Hereditary Nonpolyposis Colorectal Cancer Syndrome (or Lynch Syndrome)
Li Fraumeni syndrome
IEM Amino Acid Metabolism
Disorders of Phenylalanine Metabolism
Disorders of Tyrosine Metabolism
Disorders of Glycine Metabolism
Disorders of Proline and Hydroxyproline
Disorders of the Urea Cycle and Ornithine
Disorders of Serine Metabolism
IEM Disorders of Carbohydrate Metabolism
Disorders of Galactose Metabolism
Disorders of Fructose Metabolism
Disorders of Pentose Metabolism
Glycogen Storage Diseases
Gluconeogenic Disorders Associated with Lactic Acidosis
Congenital Disorders of Protein Glycosylation
Congenital Disorders of Protein N-Glycosylation
Congenital Disorders of Protein O-Glycosylation
Congenital Disorders of Protein N- and O-Glycosylation
Purine and Pyrimidine Metabolism
Lipoprotein and Lipid Metabolism
Monogenic Disorders of Lipoprotein Metabolism
Disorders with Primarily Elevated LDL Cholesterol
Disorders with Primarily Depressed LDL Cholesterol
Disorders with Primarily Elevated HDL Cholesterol
Disorders with Primarily Depressed HDL Cholesterol
Disorders with Primarily Elevated Triglycerides
Disorders with Multiple Lipoprotein Disturbances
Organic Acidemias and Disorders of Fatty Acid Oxidation
Organic Acidemias
Vitamin D Metabolism or Action
Hereditary Vitamin D Dependency Type 1 (VDDR-1)-1-α-Hydroxylase Deficiency
Hereditary Vitamin D-Dependent Rickets Type 2 (VDDR-2)
States Resembling Hereditary Generalized Resistance to 1,25(OH)2D
Inherited Porphyrias
Regulation of Heme Biosynthesis
Classification and Diagnosis of the Porphyrias
Inherited Disorders of Human Copper Metabolism
Menkes Disease
Wilson Disease
Iron Metabolism and Related Disorders
Syndromes of Iron Overload
Other Disorders Resulting in Derangements of Iron Handling
Mucopolysaccharidoses
Mucopolysaccharidosis I (IH Hurler, IS Scheie and IH/S Hurler–Scheie Disease)
Mucopolysaccharidosis II (Hunter Syndrome)
Mucopolysaccharidosis IIIA (Sanfilippo Syndrome, MPS IIIA)
Mucopolysaccharidosis IIIB (Sanfilippo Syndrome, MPS IIIB)
Mucopolysaccharidosis IIIC (Sanfilippo Syndrome, MPS IIIC)
Mucopolysaccharidosis IIID (Sanfilippo Syndrome, MPS IIID)
Mucopolysaccharidosis IVA and IVB (Morquio Syndrome, MPS IVA, MPS IVB)
Mucopolysaccharidosis V (Scheie Syndrome, MPS V)
Mucopolysaccharidosis VI (Maroteaux–Lamy Syndrome, MPS VI)
Mucopolysaccharidosis VII (Sly Syndrome, MPS VII)
Mucopolysaccharidosis VIII
Mucopolysaccharidosis IX (Natowicz Syndrome, MPS IX)
Oligosaccharidoses: Disorders Allied to the Oligosaccharidoses
Sphingolipid Disorders and the Neuronal Ceroid Lipofuscinoses or Batten Disease (Wolman
Disease, Cholesteryl Ester Storage Disease, and Cerebrotendinous Xanthomatosis)
GM1-Gangliosidosis (β-Galactosidosis)
GM2-Gangliosidosis
Loss-of-Function Mutation of GM3-Synthase
Niemann–Pick Disease
Niemann–Pick Disease, Types A and B
Niemann–Pick Disease, Types C and D
Farber's Disease
Acid Lipase Deficiency (Wolman Disease and Cholesteryl Ester Storage Disease)
Gaucher Disease
Galactosylceramide Lipidosis, Globoid Cell Leukodystrophy, or Krabbe Disease
Metachromatic Leukodystrophy
Fabry Disease
Neuronal Ceroid Lipofuscinosis or Batten Disease
Kufs Disease or Adult NCL
Congenital NCL/CNCL-CLN10/Cathepsin D or CTSD Deficiency
Peroxisomal Disorders
Nervous System (CNS & PNS)
Fragile X Syndrome and X-linked Intellectual Disability
Dyslexia and Related Communication Disorders
Attention-Deficit/Hyperactivity Disorder
Autism Spectrum Disorders
Genetics of Alzheimer Disease
Schizophrenia and Affective Disorders
Addictive Disorders
Neural Tube Defects
Genetic Disorders of Cerebral Cortical Development
Genetic Aspects of Human Epilepsy
Basal Ganglia Disorders (Parkinson Disease, Dystonias, Choreic Disorders)
Hereditary Ataxias (Autosomal-Dominant, Recessive, X-linked ataxias, Intermittent
Ataxias, Episodic Ataxias, Progressive Ataxias, Mitochondrial Ataxias)
Hereditary Spastic Paraplegia (Autosomal Dominant, Autosomal Recessive, X-Linked)
Autonomic and Sensory Disorders (Familial Dysautonomia, Congenital Sensory
Neuropathy with Anhidrosis)
The Phakomatoses (The Neurofibromatoses)
Tuberous sclerosis
Demyelinating Disorders (Krabbe Disease, Metachromatic & X-Linked
Adrenoleukodystrophy)
Hereditary Motor and Sensory Neuropathies (Charcot–Marie–Tooth)
Spinal Muscular Atrophies
Motor Neuron Disease: Familial Amyotrophic Lateral Sclerosis
Muscles
Muscular Dystrophies (Dystrophinopathies, Facioscapulohumeral Muscular Dystrophy
Emery–Dreifuss Muscular Dystrophies and Other Contractural Phenotypes, Limb-Girdle
Muscular Dystrophies, Myofibrillar Myopathies and Other Distal Phenotypes, Congenital
Muscular Dystrophies)
Congenital (Structural) Myopathies
Hereditary Muscle Channelopathies
Myotonic Dystrophies
Hereditary and Autoimmune Myasthenias
Eye
Color Vision Defects (Molecular Basis of Variation in Normal Color Vision, Genetics of
Red–green Color Vision in Women, Blue–Yellow (Tritan) Color Vision Defects, etc)
The Achromatopsias
Optic Atrophy
Glaucoma
Congenital Defects of the Cornea
Congenital Cataracts and Genetic Anomalies of the Lens
Hereditary Retinal and Choroidal Dystrophies: Pigmentary Retinopathies/Retinitis
Pigmentosa, Leber's Congenital Amaurosis, The Primary Cone Degenerations
Strabismus
Retinoblastoma and the RB1 Cancer Syndrome
Anophthalmia, Microphthalmia, and Uveal Coloboma
Ear: Hereditary Hearing Impairment
Clefting, Dental, and Craniofacial Syndromes
Craniosynostosis
Skin and Hair
Abnormalities of Pigmentation: Disorders of Melanosome Biogenesis/Transport—
Hermansky–Pudlak Syndrome, Chédiak–Higashi Syndrome, and Griscelli Syndrome;
Disorders of Melanocyte Survival—Vitiligo
Ichthyosiform Dermatoses
Epidermolysis Bullosa
Ectodermal Dysplasias
Xeroderma Pigmentosum
Epidermodysplasia Verruciformis
Porokeratoses
Muir–Torre Syndrome
Melanoma
Cutaneous Hamartoneoplastic Disorders: Hereditary Leiomyomatosis and Renal-Cell
Cancer, Birt–Hogg–Dubé Syndrome
Inherited Disorders of the Hair: Hypotrichosis, Hypertrichosis
Marfan Syndrome and Related Disorders
Ehlers–Danlos Syndrome
Heritable Diseases Affecting the Elastic Fibers: Cutis Laxa, Pseudoxanthoma Elasticum,
and Related Disorders
Bone
Osteogenesis Imperfecta (and Other Disorders of Bone Matrix)
Disorders of Bone Density, Volume, and Mineralization: Osteopetrosis Group of
Disorders, Raine Dysplasia, Pyknodysostosis, Dysosteosclerosis, Osteopoikilosis,
Craniotubular Remodeling Disorders, Hyperphosphatasemia with Osteoectasia, etc
Chondrodysplasias
Abnormalities of Bone Structure (Dysplasia Epiphysealis Hemimelica, Hereditary
Multiple Exostoses, Langer–Giedion Syndrome, Enchondromatosis, Maffucci Syndrome,
Metachondromatosis, Fibrous Dysplasia of Bone, etc)
Dysostoses
Arthrogryposes (Multiple Congenital Contractures)
Common Skeletal Deformities
Hereditary Noninflammatory Arthropathies
Cohesinopathies
Ciliopathies
B. Psychomotor domain:
The student should be able to understand, learn and/or perform:
1. Elicit a comprehensive medical genetic history and construct an appropriate pedigree
2. Carry out a comprehensive physical examination for major and minor anomalies, with
special attention to surface anatomy and anthropometric measurements
3. Understand prenatal diagnostic procedures both invasive (amniocentesis, chorionic
villous sampling, cordocentesis, etc) and non-invasive (fetal ultrasonography)
4. Perform fetal autopsy
5. Understand principle of cytogenetic, biochemical, and molecular laboratory methods
6. Perform specialized tests through biochemical, cytogenetic, and molecular genetic
laboratories
7. Learn interpretation of cytogenetic, biochemical, and molecular laboratory reports
8. On the basis of results, formulate an appropriate diagnosis
9. Effectively use information systems, including library and electronic resources, in the
evaluation and management of patients with genetic diseases, including diagnosis of
multiple congenital anomaly syndromes, and the recognition of teratogenic exposures.
10. Ensure that the testing is done in an Accredited Lab Only (Authenticity and legal
protection for the referring clinician). Interpretation of the results is an art and science
and hence should be included empathetically.
11. Appreciate the role of biomedical research and develop techniques for critical analysis of
current scientific developments
12. Able to coordinate information from multiple sources into a coherent and rational plan of
management of genetic disorders
13. Able to communicate and counsel patients and families who sometimes may be disturbed
and psychologically upset
14. Understand human behavior, maturation, and intelligence, in order to facilitate counseling
of varying individuals
Management of genetic diseases
The student should be able to:
1. Provide patients with access to diagnostic and predictive tests that are appropriate for the
condition in their family and advise patients of the benefits, limitations, and risks of such
tests.
2. Demonstrate use and correct interpretation of diagnostic procedures and their results
3. Advise appropriate treatments, including dietary, pharmacological, enzyme-replacement,
transplantation, and gene therapy.
4. Communicate genetic information in a manner that is suitable for each particular patient
and family. Present all available option accurately with consequences explained and non
directively.
5. Tolerate and encourage reiteration of information because of patient anxiety or
unfamiliarity with the concepts being presented
6. Apply appropriate communication techniques for conveying bad news
7. Recognize patients' defense mechanisms and be able to determine when it is better to
leave them intact and when they may need to be breached
8. Cope emotionally with responses of patients
9. Interpret their own attitudes toward ethical, social, cultural, religious, and ethnic issues
and develop an ability to individualize each patient or family member.
10. Resolve varying cultural, social, and religious attitudes in relation to issues such as
contraception, abortion, parenting, and gender roles
11. Utilize community support services and agencies appropriately
12. Plan and give an appropriate surveillance/ follow-up monitoring plan for anticipated
complications and issues
13. Understand all the associated and anticipated multisystem manifestations in order to refer
for appropriate multidisciplinary management
14. Participate in treating genetic diseases where applicable; for e.g., Lysosomal Storage
Diseases (enzyme replacement, substrate reduction & Pharmacologic Chaperone
Therapy), hypophosphatemia (burosumab), Multiple Exostoses (palovarotene),
Metaphyseal Chondrodysplasia Schmid type (carbamazepine), Osteoporosis
Pseudoglioma (lithium carbonate).
Career Options
After completing a DM in Medical Genetics, candidates will get employment opportunities in Government as well as in the Private sector.
In the Government sector, candidates have various options to choose from which include Registrar, Senior Resident, Demonstrator, Tutor etc.
While in the Private sector the options include Resident Doctor, Consultant, Visiting Consultant (Medical Genetics), Junior Consultant, Senior Consultant (Medical Genetics), Medical Genetics Specialist
Courses After DM in Medical Genetics Course
DM in Medical Genetics is a specialisation course which can be pursued after finishing a Postgraduate medical course. After pursuing specialisation in DM in Medical Genetics, a candidate could also pursue certificate courses and Fellowship programmes recognised by NMC and NBE, where DM in Medical Genetics is a feeder qualification.
Frequently Asked Question (FAQs) –DM in Medical Genetics Course
- Question: What is the full form of DM?
Answer: The full form of DM is Doctorate of Medicine
- Question: What is a DM in Medical Genetics?
Answer: DM Medical Genetics or Doctorate of Medicine in Medical Genetics also known as DM in Medical Genetics is a super specialty level course for doctors in India that is done by them after completion of their postgraduate medical degree course.
- Question: What is the duration of a DM in Medical Genetics?
Answer: DM in Medical Genetics is a super specialty programme of three years.
- Question: What is the eligibility of a DM in Medical Genetics?
Answer: Candidates must be in possession of a postgraduate medical Degree (MD/MS/DNB) from any college/university recognized by the Medical Council of India (now NMC)/NBE.
- Question: What is the scope of a DM in Medical Genetics?
Answer: DM in Medical Genetics offers candidates various employment opportunities and career prospects.
- Question: What is the average salary for a DM in Medical Genetics candidate?
Answer: The DM in Medical Genetics candidate's average salary is between Rs 5 Lakh- Rs 20 Lakh per year depending on the experience.
- Question: Can you teach after completing DM Course?
Answer: Yes, candidate can teach in a medical college/hospital after completing DM course.
- Question: What does a medical geneticist do?
Answer: Medical geneticists specialize in medicine that involves the interaction between genes and health. They are trained to evaluate, diagnose, manage, treat and counsel individuals of all ages with hereditary disorders.
