- Home
- Medical news & Guidelines
- Anesthesiology
- Cardiology and CTVS
- Critical Care
- Dentistry
- Dermatology
- Diabetes and Endocrinology
- ENT
- Gastroenterology
- Medicine
- Nephrology
- Neurology
- Obstretics-Gynaecology
- Oncology
- Ophthalmology
- Orthopaedics
- Pediatrics-Neonatology
- Psychiatry
- Pulmonology
- Radiology
- Surgery
- Urology
- Laboratory Medicine
- Diet
- Nursing
- Paramedical
- Physiotherapy
- Health news
- Fact Check
- Bone Health Fact Check
- Brain Health Fact Check
- Cancer Related Fact Check
- Child Care Fact Check
- Dental and oral health fact check
- Diabetes and metabolic health fact check
- Diet and Nutrition Fact Check
- Eye and ENT Care Fact Check
- Fitness fact check
- Gut health fact check
- Heart health fact check
- Kidney health fact check
- Medical education fact check
- Men's health fact check
- Respiratory fact check
- Skin and hair care fact check
- Vaccine and Immunization fact check
- Women's health fact check
- AYUSH
- State News
- Andaman and Nicobar Islands
- Andhra Pradesh
- Arunachal Pradesh
- Assam
- Bihar
- Chandigarh
- Chattisgarh
- Dadra and Nagar Haveli
- Daman and Diu
- Delhi
- Goa
- Gujarat
- Haryana
- Himachal Pradesh
- Jammu & Kashmir
- Jharkhand
- Karnataka
- Kerala
- Ladakh
- Lakshadweep
- Madhya Pradesh
- Maharashtra
- Manipur
- Meghalaya
- Mizoram
- Nagaland
- Odisha
- Puducherry
- Punjab
- Rajasthan
- Sikkim
- Tamil Nadu
- Telangana
- Tripura
- Uttar Pradesh
- Uttrakhand
- West Bengal
- Medical Education
- Industry
Increased lipid levels increase probability of development of Trigger Finger
Trigger finger, a condition known for causing pain and stiffness in the fingers, especially among people aged 50 to 60 years, has been a source of discomfort for many. A new breakthrough published in the Public Library of Science has shed light on a potential cause of this common ailment, as a large-scale population-based study suggests that hyperlipidemia may be linked to trigger finger.
Trigger finger, also referred to as stenosing tenosynovitis, affects approximately 3% of the general population. Its primary symptoms include pain, locking, or tightness at the base of one or more fingers. Often, the thumb and fourth finger are the most affected. Patients commonly report a popping or catching sensation when extending their fingers from a flexed position, accompanied by the presence of a palpable nodule during physical examination.
Pei-Tsen Chen and team conducted a nationwide population-based cohort study using longitudinal data from 2000 to 2013. The study included 41,421 patients with hyperlipidemia and 82,842 age- and sex-matched individuals in the control cohort, with an average age of approximately 50 years.
The results of the study revealed a compelling correlation between hyperlipidemia and trigger finger. After adjusting for potential comorbidities, the researchers found that the hazard ratio of trigger finger in the hyperlipidemia cohort was 4.03 (95% confidence interval [CI], 3.57–4.55). The correlation was further broken down by gender, with male patients showing a hazard ratio of 4.59 (95% CI, 3.67–5.73) and female patients a hazard ratio of 3.77 (95% CI, 3.26–4.36). These findings suggest that the association between hyperlipidemia and trigger finger is consistent across both sexes, albeit slightly more pronounced in males.
The exact mechanism by which hyperlipidemia contributes to trigger finger remains uncertain. However, the researchers hypothesize that elevated lipid levels might lead to reduced blood supply in the distal fingers, promoting inflammation. This inflammation could hinder the smooth gliding of the flexor tendon within the tendon sheath, resulting in the characteristic symptoms of trigger finger. For individuals with hyperlipidemia, it may be prudent to be vigilant about any symptoms related to trigger finger and seek medical advice promptly if concerns arise.
Source:
Chen, P.-T., Zhang, H.-W., Tsai, Z.-R., Peng, H.-C., Lin, Y.-S., Tsai, J. J. P., & Lin, C.-W. (2023). Association between hyperlipidemia and trigger finger: A nationwide population-based cohort study. In P. Chaudhary (Ed.), PLOS ONE (Vol. 18, Issue 7, p. e0288426). Public Library of Science (PLoS). https://doi.org/10.1371/journal.pone.0288426
Neuroscience Masters graduate
Jacinthlyn Sylvia, a Neuroscience Master's graduate from Chennai has worked extensively in deciphering the neurobiology of cognition and motor control in aging. She also has spread-out exposure to Neurosurgery from her Bachelor’s. She is currently involved in active Neuro-Oncology research. She is an upcoming neuroscientist with a fiery passion for writing. Her news cover at Medical Dialogues feature recent discoveries and updates from the healthcare and biomedical research fields. She can be reached at editorial@medicaldialogues.in
Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751