Medical Dialogues
  • Dermatology
Login Register
This site is intended for healthcare professionals only
Login Register
  • Medical Jobs
  • Medical Matrimony
  • MD Brand Connect
  • MDTV
    • Breaking News
    • Medical News Today
    • Health News Today
    • Latest
    • Journal Club
    • Medico Legal Update
    • Latest Webinars
    • MD Shorts
    • Health Dialogues
Medical Dialogues
  • Medical News & Guidelines
      • Anesthesiology
      • Cardiology and CTVS
      • Critical Care
      • Dentistry
      • Dermatology
      • Diabetes and Endocrinology
      • ENT
      • Gastroenterology
      • Medicine
      • Nephrology
      • Neurology
      • Obstretics-Gynaecology
      • Oncology
      • Ophthalmology
      • Orthopaedics
      • Pediatrics-Neonatology
      • Psychiatry
      • Pulmonology
      • Radiology
      • Surgery
      • Urology
      • Laboratory Medicine
      • Diet
      • Nursing
      • Paramedical
      • Physiotherapy
  • Health news
      • Doctor News
      • Government Policies
      • Hospital & Diagnostics
      • International Health News
      • MCI News
      • Medical Organization News
      • Medico Legal News
      • NBE News
      • NMC News
  • AYUSH
    • Ayurveda
    • Homeopathy
    • Siddha
    • Unani
    • Yoga
  • State News
      • Andaman and Nicobar Islands
      • Andhra Pradesh
      • Arunachal Pradesh
      • Assam
      • Bihar
      • Chandigarh
      • Chattisgarh
      • Dadra and Nagar Haveli
      • Daman and Diu
      • Delhi
      • Goa
      • Gujarat
      • Haryana
      • Himachal Pradesh
      • Jammu & Kashmir
      • Jharkhand
      • Karnataka
      • Kerala
      • Ladakh
      • Lakshadweep
      • Madhya Pradesh
      • Maharashtra
      • Manipur
      • Meghalaya
      • Mizoram
      • Nagaland
      • Odisha
      • Puducherry
      • Punjab
      • Rajasthan
      • Sikkim
      • Tamil Nadu
      • Telangana
      • Tripura
      • Uttar Pradesh
      • Uttrakhand
      • West Bengal
  • Medical Education
      • Ayush Education News
      • Dentistry Education News
      • Medical Admission News
      • Medical Colleges News
      • Medical Courses News
      • Medical Universities News
      • Nursing education News
      • Paramedical Education News
      • Study Aborad
  • Industry
      • Health Investment News
      • Health Startup News
      • Medical Devices News
      • Pharma News
      • Pharmacy Education News
      • Industry Perspective
  • MDTV
      • Health Dialogues MDTV
      • Health News today MDTV
      • Latest Videos MDTV
      • Latest Webinars MDTV
      • MD shorts MDTV
      • Medical News Today MDTV
      • Medico Legal Update MDTV
      • Top Videos MDTV
      • Health Perspectives MDTV
      • Journal Club MDTV
This site is intended for healthcare professionals only
LoginRegister
Medical Dialogues
LoginRegister
  • Home
  • Medical news & Guidelines
    • Anesthesiology
    • Cardiology and CTVS
    • Critical Care
    • Dentistry
    • Dermatology
    • Diabetes and Endocrinology
    • ENT
    • Gastroenterology
    • Medicine
    • Nephrology
    • Neurology
    • Obstretics-Gynaecology
    • Oncology
    • Ophthalmology
    • Orthopaedics
    • Pediatrics-Neonatology
    • Psychiatry
    • Pulmonology
    • Radiology
    • Surgery
    • Urology
    • Laboratory Medicine
    • Diet
    • Nursing
    • Paramedical
    • Physiotherapy
  • Health news
    • Doctor News
    • Government Policies
    • Hospital & Diagnostics
    • International Health News
    • MCI News
    • Medical Organization News
    • Medico Legal News
    • NBE News
    • NMC News
  • AYUSH
    • Ayurveda
      • Ayurveda Giuidelines
      • Ayurveda News
    • Homeopathy
      • Homeopathy Guidelines
      • Homeopathy News
    • Siddha
      • Siddha Guidelines
      • Siddha News
    • Unani
      • Unani Guidelines
      • Unani News
    • Yoga
      • Yoga Guidelines
      • Yoga News
  • State News
    • Andaman and Nicobar Islands
    • Andhra Pradesh
    • Arunachal Pradesh
    • Assam
    • Bihar
    • Chandigarh
    • Chattisgarh
    • Dadra and Nagar Haveli
    • Daman and Diu
    • Delhi
    • Goa
    • Gujarat
    • Haryana
    • Himachal Pradesh
    • Jammu & Kashmir
    • Jharkhand
    • Karnataka
    • Kerala
    • Ladakh
    • Lakshadweep
    • Madhya Pradesh
    • Maharashtra
    • Manipur
    • Meghalaya
    • Mizoram
    • Nagaland
    • Odisha
    • Puducherry
    • Punjab
    • Rajasthan
    • Sikkim
    • Tamil Nadu
    • Telangana
    • Tripura
    • Uttar Pradesh
    • Uttrakhand
    • West Bengal
  • Medical Education
    • Ayush Education News
    • Dentistry Education News
    • Medical Admission News
    • Medical Colleges News
    • Medical Courses News
    • Medical Universities News
    • Nursing education News
    • Paramedical Education News
    • Study Aborad
  • Industry
    • Health Investment News
    • Health Startup News
    • Medical Devices News
    • Pharma News
      • CDSCO (Central Drugs Standard Control Organisation) News
    • Pharmacy Education News
    • Industry Perspective
  • Home
  • Nephrology
  • Nephrology News
  • Children with CKD have...

Children with CKD have elevated disease burden including fatigue and sleep problems

Written by Jacinthlyn Sylvia Published On 2023-03-10T20:00:30+05:30  |  Updated On 11 March 2023 7:32 AM GMT
Children with CKD have elevated disease burden including fatigue and sleep problems
  • facebook
  • twitter
  • linkedin
  • whatsapp
  • Telegram
  • koo
  • Email

A new study by Sandra Amaral and team found that independent of the severity of the disease, children with chronic kidney disease (CKD) have significant but steady burden of impairment across several patient-reported outcomes (PROs) measures, including tiredness and global health. The findings of this study were published in the American Journal of Kidney Diseases.Children with chronic...

A new study by Sandra Amaral and team found that independent of the severity of the disease, children with chronic kidney disease (CKD) have significant but steady burden of impairment across several patient-reported outcomes (PROs) measures, including tiredness and global health.

The findings of this study were published in the American Journal of Kidney Diseases.

Children with chronic renal illness have a poorly understood lived experience. In order to determine how clinical outcomes in children with CKD compare to those in other children, researchers looked at the relationships between patient-reported outcomes (PROs) measuring children's fatigue, psychological distress, family relationships, sleep health, and overall health and clinical outcomes over time.

A total of 212 CKD-affected children aged 8 to 21 and their parents were enrolled in this prospective cohort trial, which was conducted throughout 16 nephrology programs in North America. The key predictors in this study were CKD stage, sociodemographic characteristics, illness etiology, and clinical factors. For a period of two years, the outcomes were evaluated. To do this, researchers compared PROs in the CKD group with a general pediatric population that was considered to be nationally representative. Using multivariable regression models, it was determined how PROs changed over time and how sociodemographic and clinical factors were related to PROs.

The key findings of this study were:

1. During all times, 84% of parents and 77% of kids completed PROs.

2. In comparison to the general pediatric population, children with CKD had baseline PRO scores that showed higher burdens of fatigue, psychological distress, impaired global health, sleep-related impairment, and poorer family relationships, with median score differences for fatigue and global health being one standard deviation.

3. By stage of CKD or between glomerular and non-glomerular etiologies, baseline PRO scores did not vary.

4. Over the course of two years, PROs exhibited great stability, with an average yearly change on each measure of less than one point and intraclass correlation coefficients ranging from 0.53 to 0.79.

5. Worse ratings for exhaustion, psychological health, and overall health were connected with hospitalization and parent-reported sleep issues.

Reference:

Amaral, S., Schuchard, J., Claes, D., Dart, A., Greenbaum, L. A., Massengill, S. F., Atkinson, M. A., Flynn, J. T., Dharnidharka, V. R., Fathallah-Shaykh, S., Yadin, O., Modi, Z. J., Al-Uzri, A., Wilson, A. C., Dell, K. M., Patel, H. P., Bruno, C., Warady, B., Furth, S., & Forrest, C. B. (2023). Patient-Reported Outcomes Over 24 Months in Pediatric CKD: Findings From the MyKidneyHealth Cohort Study. In American Journal of Kidney Diseases. Elsevier BV. https://doi.org/10.1053/j.ajkd.2022.12.014

American Journal of Kidney DiseasesChronic kidney diseasePatient reported outcomes measures
Source : American Journal of Kidney Diseases
Jacinthlyn Sylvia
Jacinthlyn Sylvia

    Neuroscience Masters graduate

    Jacinthlyn Sylvia, a Neuroscience Master's graduate from Chennai has worked extensively in deciphering the neurobiology of cognition and motor control in aging. She also has spread-out exposure to Neurosurgery from her Bachelor’s. She is currently involved in active Neuro-Oncology research. She is an upcoming neuroscientist with a fiery passion for writing. Her news cover at Medical Dialogues feature recent discoveries and updates from the healthcare and biomedical research fields. She can be reached at editorial@medicaldialogues.in

    Show Full Article
    Next Story
    Similar Posts
    NO DATA FOUND

    Editorial

    Journal Club Today

    Health News Today

    © 2022 All Rights Reserved.
    Powered By: Hocalwire
    X
    X