Kidney Stones Linked to Higher Cardiovascular Disease Risk, finds research

Written by Dr Kartikeya Kohli Published On 2025-03-05T20:45:05+05:30 | Updated On 6 March 2025 11:42 AM IST

Kidney Stones Linked to Higher Cardiovascular Disease Risk, finds research

New Research indicates a high prevalence of kidney stones and their association with increased cardiovascular disease (CVD) risk. Further factors such as gender, age, and kidney stone history contribute to a higher likelihood of developing CVD.

Since the prevalence of kidney stones and cardiovascular diseases (CVD) is increasing globally and also in Iran, it is vital to assess the associations between both disorders. The current study aimed to investigate the association between kidney stones and the risk of CVD.

This study was cross-sectional in design, which used the data of the Rafsanjan cohort study (RCS), a population-based Prospective epidemiological research study in Iran (PERSIAN) that recruited 10,000 participants of both genders aged 35–70 years from four urban and suburban areas of Rafsanjan. Demographic factors, medical history, personal habits, and biochemical parameters, including Fasting blood sugar (FBS), glomerular filtration rate (GFR), creatine (Cr), Blood urea nitrogen (BUN), urine specific gravity (USG), and lipids of the participant,s were collected according to standard protocols.

Results: The results showed that the risk of CVD was higher in men (51.02%) than in women (48.98%). Also, the results showed the highest risk of CVD development for age ≥ 56 years old. The results were presented in about 31% of patients with kidney stones, 19.5% of patients with abnormal urine tests, 9.84% with Proteinuria, more than 33% with abnormal USG, and more than 94% of patients with abnormal GFR had CVD. The odds of CVD were increased in patients with kidney stones (22%), female (25%), and age ≥ 56 years old (24%).

There was a high prevalence of kidney stones and CVD risk factors, such as gender, age, and kidney stones that increased the risk of cardiovascular disease.

Reference:

Nazari, A., Jamali, Z., Soltani, N. et al. Kidney stone and risk of cardiovascular diseases: a cross-sectional study in the southeast of Iran. BMC Nephrol 26, 101 (2025). https://doi.org/10.1186/s12882-025-04018-1

Kidney StonesLinkedHigherCardiovascularDiseaseRiskfinds research

Source : BMC Nephrology

Dr Kartikeya Kohli

Dr Kartikeya Kohli is an Internal Medicine Consultant at Sitaram Bhartia Hospital in Delhi with super speciality training in Nephrology. He has worked with various eminent hospitals like Indraprastha Apollo Hospital, Sir Gangaram Hospital. He holds an MBBS from Kasturba Medical College Manipal, DNB Internal Medicine, Post Graduate Diploma in Clinical Research and Business Development, Fellow DNB Nephrology, MRCP and ECFMG Certification. He has been closely associated with India Medical Association South Delhi Branch and Delhi Medical Association and has been organising continuing medical education programs on their behalf from time to time. Further he has been contributing medical articles for their newsletters as well. He is also associated with electronic media and TV for conduction and presentation of health programs. He has been associated with Medical Dialogues for last 3 years and contributing articles on regular basis.