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Study Finds Significant Link Between Serum Magnesium Levels and Carotid Atherosclerosis in hemodialysis patients

Written By : Dr. Shravani Dali |Medically Reviewed By : Dr. Kamal Kant Kohli Published On 2025-06-20T21:00:00+05:30  |  Updated On 21 Jun 2025 11:44 AM IST
Study Finds Significant Link Between Serum Magnesium Levels and Carotid Atherosclerosis in hemodialysis patients
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Researchers in a new study have found significant association between serum magnesium (Mg) levels and carotid intima-media thickness (CIMT), suggesting a connection between magnesium levels and carotid atherosclerosis.

They aimed to examine whether serum magnesium level is related to cardiovascular events in hemodialysis patients by investigating the relationship between serum magnesium (Mg) level and carotid intima media thickness (CIMT). In this cross-sectional study, we evaluated 88 hemodialysis patients.

The mean CIMT of these patients was measured and recorded by doppler ultrasonography. Patients were divided into two groups according to their serum magnesium level. Correlation analysis and linear regression analysis were used to define the relationship between study parameters.

We divided our patients into 2 groups according to Mg value as group 1 (Mg ≥ 2.3 mg/dl) and group 2 (Mg < 2.3 mg/dl).

Results: The mean CIMT of patients with group 1 and group 2 were respectively 0.93 ± 0.22 mm and 1.03 ± 0.22 mm. There was statistically significant difference between two groups in terms of the mean CIMT value (p = 0.045). We found negative, low-level, statistically significant correlations between Mg and mean CIMT ​​(r=-0.272; p = 0.010), calcium and mean CIMT (r: -0.221, p: 0.039) and hemoglobin and mean CIMT (r: -0.215, p: 0.044).

According to regression analysis, serum magnesium level and age were found independent risk factors for mean CIMT value (p: 0.004 and p: 0.045). They found a significant relationship between serum Mg level and CIMT, which indicates carotid atherosclerosis.

Reference:

Kara, A.V., Ozdemir, R., Inan, H. et al. Effect of serum magnesium level on carotid intima media thickness in hemodialysis patients. BMC Nephrol 26, 270 (2025). https://doi.org/10.1186/s12882-025-04168-2

StudyFindsSignificantLinkBetweenSerumMagnesiumLevelsCarotid Atherosclerosis
Source : BMC Nephrology
Dr. Shravani Dali
Dr. Shravani Dali

    Dr. Shravani Dali has completed her BDS from Pravara institute of medical sciences, loni. Following which she extensively worked in the healthcare sector for 2+ years. She has been actively involved in writing blogs in field of health and wellness. Currently she is pursuing her Masters of public health-health administration from Tata institute of social sciences. She can be contacted at editorial@medicaldialogues.in.

    Dr. Kamal Kant Kohli
    Dr. Kamal Kant Kohli

    Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751

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