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Mylab Discovery Solutions, DnaNudge ink pact for development of next-generation molecular diagnostics for diabetic foot infections

Ruchika SharmaWritten by Ruchika Sharma Published On 2023-03-13T16:57:42+05:30  |  Updated On 13 March 2023 4:57 PM IST
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DnaNudge's new multiplex tests will enable health teams to quickly identify the specific microbiological organisms responsible for each foot infection, providing antimicrobial resistance results in just over an hour.

London: DnaNudge has announced a strategic partnership with India’s biotech company Mylab Discovery Solutions to develop next-generation molecular diagnostics for diabetic foot infections and other key health conditions. The first delivery from this partnership is an innovative diabetic foot ulcer detection kit to help clinicians rapidly identify bacteria involved in infections and optimally treat patients at the point of decision – reducing the risks of acute complications, limb amputation and antimicrobial resistance (AMR).

Imperial College London spin-out DnaNudge and Mylab marked the agreement with a formal signing in the presence of Dr. Thaksin Shinawatra, Former Prime Minister of Thailand and Yingluck Shinawatra, Former Prime Minister of Thailand.

The diabetic foot ulcer detection kit is expected to be available in India in Q2 2023. India has a diabetic population of 80 million, and almost 25 percent of these patients are at risk of developing an infected foot ulcer – one of the most common complications of diabetes mellitus – leading to frequent hospitalisation and in some cases, lower limb amputation. Studies have shown that many of the bacteria in foot ulcers are resistant to commonly used antibiotics. The complete identification of bacteria present in wounds is difficult with traditional culture methods, which are not able to fully reveal the presence of bacterial diversity.

DnaNudge’s new multiplex tests will enable health teams to quickly identify the specific microbiological organisms responsible for each foot infection, providing antimicrobial resistance results in just over an hour. This innovation will enable clinicians to optimally treat patients with the most appropriate antibiotics, reducing the risk of AMR, which now represents a major threat to global public health. The first ever comprehensive analysis of the global impact of antimicrobial resistance has estimated that resistance itself caused 1.27 million deaths in 2019 – more deaths than either HIV/AIDS or malaria – and that antimicrobial-resistant infections played a role in 4.95 million deaths (Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis, published in The Lancet, January 2022).

Under the terms of the partnership DnaNudge and Mylab will work together to develop innovative new multiplex tests for other targeted conditions, harnessing DnaNudge’s lab-free testing platform technology. DnaNudge’s technology was instrumental in the fight against COVID-19 in the UK. DnaNudge’s portable NudgeBox analyser and highly multiplexed DnaCartridge test cartridges deliver highly accurate results in around just an hour – without the need for a laboratory.

Commenting on the MoU, MD of Mylab Discovery Solutions Hasmukh Rawal said: “This partnership marks another milestone in our journey towards making cutting-edge molecular diagnostics available in the world. Together, with DnaNudge’s deep expertise in point-of-care genetics testing technology, we will be able to present precise and high-quality diagnostic solutions within the reach of every person across the world.”

He added: “Diabetes Mellitus is known to have many complications and one of the most distressing is diabetic foot ulcer which affects 25 percent of people with diabetes. It puts enormous financial burden on the patient and the health care services, even though it is preventable. The diabetic foot ulcer detection kit promises to improve foot ulcer diagnosis and identify appropriate treatment approaches that will promote the curing in a timely manner.”

Commenting on the collaboration, Regius Professor Chris Toumazou FRS FREng FMedSci, co-founder of DnaNudge and founder of the Institute of Biomedical Engineering at Imperial College London said, “This collaboration to deliver one of the world’s first point-of-decision technologies is a stand-out example of how India and the UK are working closely together to create transformative breakthroughs in medical technology. DnaNudge and Mylab share a vision to deliver effective and collaborative solutions to global health challenges, and Mylab’s proven excellence in R&D and delivery mirrors our ambition to deliver near-patient diagnostics that can significantly – and sustainably – improve people’s lives everywhere.”

Keeley Foley, Director of DnaNudge and Specialist Diabetic Foot Podiatrist PhD candidate added: “Together, leveraging India’s first-class medical diagnostics capabilities, we aim to rapidly bring to the global market next-generation medical and consumer tests in the areas of most need – from antimicrobial resistance, diabetes and nutrition to many other serious public health challenges. DnaNudge’s unique enabling technology delivers highly accurate multiplex testing capabilities, right at the point of clinical need, and where it can potentially create the most life-changing impacts for patients – saving lives and limbs.”

According to the World Health Organisation, around 422 million people worldwide have diabetes and 1.5 million deaths are directly attributed to diabetes each year. In India, the number of people with diabetes is expected to increase to 135 million by 2045.

Read also: Mylab Discovery Solutions unveils combined RT-PCR test kit for chikungunya, dengue, malaria

DnaNudgeMylab Discovery Solutionsdiabetic foot ulcer detection kit
Ruchika Sharma
Ruchika Sharma

    Ruchika Sharma joined Medical Dialogue as an Correspondent for the Business Section in 2019. She covers all the updates in the Pharmaceutical field, Policy, Insurance, Business Healthcare, Medical News, Health News, Pharma News, Healthcare and Investment. She has completed her B.Com from Delhi University and then pursued postgraduation in M.Com. She can be contacted at editorial@medicaldialogues.in Contact no. 011-43720751

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