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  • Oxford stops dosing in...

Oxford stops dosing in AstraZeneca Covid vaccine trial, awaiting additional safety review

Ruchika SharmaWritten by Ruchika Sharma Published On 2021-04-07T15:50:33+05:30  |  Updated On 7 April 2021 3:50 PM IST
Oxford stops dosing in AstraZeneca Covid vaccine trial, awaiting additional safety review
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New Delhi: Researchers at Oxford University have paused an ongoing pediatric clinical trial of the coronavirus vaccine it is developing with AstraZeneca. In an official statement, the university said that it is awaiting the results of a safety review from UK regulators, the Medicines and Healthcare products Regulatory Agency (MHRA), as reported by the Hill.

An Oxford spokesperson said "there are no safety concerns concerning the pediatric research, but the trial is paused while they await additional information from MHRA," "which is reviewing possible links between the vaccine and rare blood clots in adults," the spokesperson added.
The trial is testing the effectiveness of the vaccine in up to 300 children between the ages of 6 and 17.
"Whilst there are no safety concerns in the pediatric clinical trial, we await additional information from the MHRA on its review of rare cases of thrombosis /thrombocytopaenia that have been reported in adults, before giving any further vaccinations in the trial," the university said.
The trial pause is the latest development in the ongoing saga over the AstraZeneca vaccine, which has not had a smooth rollout overseas.
Concerns over the blood clotting events in a small number of recipients have dogged the shot in recent weeks and resulted in more than a dozen European countries temporarily suspending the use of the vaccine last month while waiting on the European regulatory agency's recommendations on how to proceed, The Hill reported.
The European Medicines Agency (EMA) endorsed the safety of the shot but said it could not rule out a link to the blood clots and would add a warning to the product in order to draw attention to the possibility of such rare side effects.
Many European countries are relying heavily on the Oxford-AstraZeneca vaccine, as it is being sold using a nonprofit model and is far cheaper to make than other Covid-19 vaccines. The vaccine is authorized for adults age 18 and older overseas, but the company has not yet filed for emergency authorization in the US.

Read also: UK: Benefits outweigh risks for AstraZeneca despite 7 deaths



oxford universityastrazeneca newsastrazenecacoronavirus vaccinecoronaviruscovid-19
Source : ANI
Ruchika Sharma
Ruchika Sharma

    Ruchika Sharma joined Medical Dialogue as an Correspondent for the Business Section in 2019. She covers all the updates in the Pharmaceutical field, Policy, Insurance, Business Healthcare, Medical News, Health News, Pharma News, Healthcare and Investment. She has completed her B.Com from Delhi University and then pursued postgraduation in M.Com. She can be contacted at editorial@medicaldialogues.in Contact no. 011-43720751

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