Pregnant patients with TA at increased risk for adverse pregnancy outcomes

Written By : Jacinthlyn Sylvia |Medically Reviewed By : Dr. Kamal Kant Kohli Published On 2023-03-01T10:00:24+05:30 | Updated On 1 March 2023 3:04 PM IST

A recent study published in the Nature Scientific Reports found that women with Takayasu arteritis (TA) have increased risk of adverse pregnancy outcomes than general population.

Takayasu arteritis (large vessel vasculitis) is a rare autoimmune disease that affects the aorta and its branches, mainly in young women. Due to its systemic nature, pregnancies in TA patients are at high risk of adverse outcomes. There is limited information on the incidence of adverse pregnancy events in these patients. So, Styliani Partalidou and team undertook this study to evaluate the prevalence of adverse pregnancy outcomes, including miscarriage, hypertension, and pre-eclampsia, in women with TA. The researchers conducted a systematic review and meta-analysis of 27 studies, which included a total of 825 pregnancies in TA patients.

The key findings of the study were:

The prevalence of adverse pregnancy outcomes in TA patients was high.

The occurrence of miscarriage was 16%, hypertension was 37%, and pre-eclampsia was 14%, which in turn indicate that TA patients have a higher risk of adverse pregnancy outcomes than the general population.

Also, close monitoring is essential for pregnant women with TA to ensure the best possible outcomes.

It is also essential to develop and implement management strategies that can improve pregnancy outcomes in TA patients.

The study has some limitations, including the possibility of publication bias and heterogeneity among the studies analyzed. The quality of the studies included in the analysis was also variable, and some studies had a small sample size. Despite these limitations, this study provides important insights into the prevalence of adverse pregnancy outcomes in women with TA and highlights the need for close monitoring and effective management strategies.

Source:

Partalidou, S., Mamopoulos, A., Dimopoulou, D., & Dimitroulas, T. (2023). Pregnancy outcomes in Takayasu arteritis patients: a systematic review and meta-analysis. In Scientific Reports (Vol. 13, Issue 1). Springer Science and Business Media LLC.https://doi.org/10.1038/s41598-023-27379-9

Scientific Reportstakayasu arteritisadverse pregnancy outcomes

Source : Nature Scientific Reports

Jacinthlyn Sylvia

Neuroscience Masters graduate

Jacinthlyn Sylvia, a Neuroscience Master's graduate from Chennai has worked extensively in deciphering the neurobiology of cognition and motor control in aging. She also has spread-out exposure to Neurosurgery from her Bachelor’s. She is currently involved in active Neuro-Oncology research. She is an upcoming neuroscientist with a fiery passion for writing. Her news cover at Medical Dialogues feature recent discoveries and updates from the healthcare and biomedical research fields. She can be reached at editorial@medicaldialogues.in

Dr. Kamal Kant Kohli

Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751