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  • Incomplete resection...

Incomplete resection of colorectal polyps associated with neoplasia recurrence: Study

MD Editorial TeamWritten by MD Editorial Team Published On 2021-10-16T09:00:17+05:30  |  Updated On 16 Oct 2021 3:30 AM GMT
Incomplete resection of colorectal polyps associated with  neoplasia recurrence: Study
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USA: Researchers have discovered a statistically substantially higher incidence of future neoplasia and advanced neoplasia in colon segments after partial resection compared to segments with complete resection. The findings of this study were published in the American College of Physicians, Annals of Internal Medicine on 10th August 2021.Incomplete excision of neoplastic polyps is thought to be...

USA: Researchers have discovered a statistically substantially higher incidence of future neoplasia and advanced neoplasia in colon segments after partial resection compared to segments with complete resection. The findings of this study were published in the American College of Physicians, Annals of Internal Medicine on 10th August 2021.

Incomplete excision of neoplastic polyps is thought to be a major cause of colorectal cancer development. However, there is little information on the natural history of polyps that has been partially excised. To fill this knowledge gap, Heiko Pohl and the team conducted an observational cohort study between 2009 to 2012, with the objective of determining the risk of metachronous neoplasia during a surveillance colonoscopy following a reported partial polyp excision.

The proportion of colon segments with at least one neoplastic polyp at the initial surveillance examination was evaluated as segment metachronous neoplasia. Segment metachronous neoplasia was compared between segments that had a prior incomplete polyp resection (incomplete segments) and those that had a prior complete resection (full segments), taking into consideration segment clustering among individuals. Patients with a 5- to 20-mm malignant polyp excision, a documented complete or partial resection, and a surveillance examination were included.

In the original study, 166 of the 233 individuals received at least one surveillance assessment. After partial resection, the median time to surveillance was shorter than after full resection (median, 17 vs. 45 months). The probability of developing any metachronous neoplasia was higher in parts with partial resection vs full resection. Incomplete segments also had more neoplastic polyps and a higher likelihood of advanced neoplasia. The greatest independent factor linked with metachronous neoplasia was incomplete resection.

Reference:

Pohl, H., Anderson, J. C., Aguilera-Fish, A., Calderwood, A. H., Mackenzie, T. A., & Robertson, D. J. (2021). Recurrence of Colorectal Neoplastic Polyps After Incomplete Resection. Annals of Internal Medicine. https://doi.org/10.7326/m20-6689

Colorectal PolypsAnnals of Internal Medicineresection
Source : Annals of Internal Medicine
MD Editorial Team
MD Editorial Team

    Medical Dialogues consists of a team of passionate medical/scientific writers, led by doctors and healthcare researchers. Our team efforts to bring you updated and timely news about the important happenings of the medical and healthcare sector. Our editorial team can be reached at editorial@medicaldialogues.in.

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