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  • Long term consumption...

Long term consumption of dark chocolate beneficial in preventing retinal vascular disease, reveals research

Dr. Shravani DaliWritten by Dr. Shravani Dali Published On 2024-10-20T21:15:15+05:30  |  Updated On 20 Oct 2024 9:15 PM IST
Long term consumption of dark chocolate beneficial in preventing retinal vascular disease, reveals research
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Research published in Scientific Reports reveals that long-term consumption of dark chocolate is beneficial in preventing retinal vascular disease.

There is a lack of knowledge about the effect of flavanols-rich dark chocolate intake on the anatomy and functionality of retinal vessels. The aim of this study prospective, randomized, blind, crossover clinical trial (ClinicalTrials.gov Identifier: NCT05227248, 07/02/2022) was to evaluate the effect of dark-chocolate intake on the functionality and anatomy of the retinal vessels in healthy subjects using dynamic vessel analyzer (DVA) and optical coherence tomography angiography (OCT-A). Twenty eyes of 20 healthy subjects (mean age, 24.4 ± 1.6 years; 12 females) were enrolled. Participants were randomized to consume 20 g of dark chocolate or 7.5 g of milk chocolate. Visual function, DVA and OCT-A parameters were evaluated before chocolate consumption and two hours later. One week later, the same participants were tested before and after consuming the opposite chocolate. Using OCT-A, no differences were disclosed in terms of perfusion density changes after dark-chocolate and milk-chocolate intake analyzing all chorioretinal plexuses (p > 0.09 in all analyses). Using DVA, a significant increase in the arterial dilation percentage after flicker stimulation was disclosed comparing baseline (2.750 ± 2.054%) with values after the dark chocolate intake (4.145 ± 3.055%, p = 0.016). This difference was not disclosed after the milk chocolate intake (p = 0.465). We disclosed that a reasonable amount of flavanols-rich chocolate in healthy subjects has benefic functional short-term effects in retinal vessels measured with DVA. This suggests a potential role of dark chocolate intake on retinal vessels. Further studies with long-term follow-up are warranted to show if the chronic assumption of dark chocolate could play a favorable role in the prevention of retinal diseases.


Reference:

Sacconi, R., Pezzella, M., Ribarich, N. et al. Benefits of dark chocolate intake on retinal vessels functionality: a randomized, blind, crossover clinical trial. Sci Rep 14, 20203 (2024). https://doi.org/10.1038/s41598-024-70289-7

Keywords:

Long term, consumption, dark chocolate, beneficial, preventing, retinal, vascular, disease, reveals, research, Scientific Reports, Sacconi, R., Pezzella, M., Ribarich, N.







Long termconsumptiondark chocolatebeneficialpreventingretinalvasculardiseaserevealsresearch
Source : Scientific Reports
Dr. Shravani Dali
Dr. Shravani Dali

    Dr. Shravani Dali has completed her BDS from Pravara institute of medical sciences, loni. Following which she extensively worked in the healthcare sector for 2+ years. She has been actively involved in writing blogs in field of health and wellness. Currently she is pursuing her Masters of public health-health administration from Tata institute of social sciences. She can be contacted at editorial@medicaldialogues.in.

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