- Home
- Medical news & Guidelines
- Anesthesiology
- Cardiology and CTVS
- Critical Care
- Dentistry
- Dermatology
- Diabetes and Endocrinology
- ENT
- Gastroenterology
- Medicine
- Nephrology
- Neurology
- Obstretics-Gynaecology
- Oncology
- Ophthalmology
- Orthopaedics
- Pediatrics-Neonatology
- Psychiatry
- Pulmonology
- Radiology
- Surgery
- Urology
- Laboratory Medicine
- Diet
- Nursing
- Paramedical
- Physiotherapy
- Health news
- Fact Check
- Bone Health Fact Check
- Brain Health Fact Check
- Cancer Related Fact Check
- Child Care Fact Check
- Dental and oral health fact check
- Diabetes and metabolic health fact check
- Diet and Nutrition Fact Check
- Eye and ENT Care Fact Check
- Fitness fact check
- Gut health fact check
- Heart health fact check
- Kidney health fact check
- Medical education fact check
- Men's health fact check
- Respiratory fact check
- Skin and hair care fact check
- Vaccine and Immunization fact check
- Women's health fact check
- AYUSH
- State News
- Andaman and Nicobar Islands
- Andhra Pradesh
- Arunachal Pradesh
- Assam
- Bihar
- Chandigarh
- Chattisgarh
- Dadra and Nagar Haveli
- Daman and Diu
- Delhi
- Goa
- Gujarat
- Haryana
- Himachal Pradesh
- Jammu & Kashmir
- Jharkhand
- Karnataka
- Kerala
- Ladakh
- Lakshadweep
- Madhya Pradesh
- Maharashtra
- Manipur
- Meghalaya
- Mizoram
- Nagaland
- Odisha
- Puducherry
- Punjab
- Rajasthan
- Sikkim
- Tamil Nadu
- Telangana
- Tripura
- Uttar Pradesh
- Uttrakhand
- West Bengal
- Medical Education
- Industry
Optimal Intra-operative Mitomycin C Dose improves success of Microshunt Implantation among Glaucoma Patients
A recent multicenter retrospective cohort study involved 250 eyes from 220 glaucoma patients and identified the factors influencing the success of Microshunt implantation. This study was designed to evaluate risk factors for Microshunt failure, and found the crucial elements that could enhance surgical outcomes for glaucoma patients. The findings were published in American Journal of Ophthalmology.
The success criteria were defined based on intraocular pressure (IOP) outcomes, ranging from a reduction to as low as 12mmHg. At the 1-year follow-up, success rates varied between 43.3% and 62.5%, depending on the specific criteria. Notably, the concentration of mitomycin-C (MMC) during surgery emerged as a key determinant. Higher intraoperative MMC concentration was associated with a significantly reduced risk of failure for both complete and overall success.
The study showed other risk factors contributing to Microshunt failure. Pseudoexfoliation glaucoma/pigmentary glaucoma, primary angle-closure glaucoma, and a history of non-glaucomatous ocular surgeries increased the risk of failure for complete success. For overall success, factors such as lower preoperative IOP, a higher number of preoperative antiglaucoma agents, and the combination of Microshunt with cataract surgery were identified as significant risk factors.
These findings underscore the need for precision in surgical approaches and highlight the intricate balance required for optimal outcomes. The study not only provides critical insights into factors influencing Microshunt efficacy but also emphasizes the importance of personalized patient selection for these procedures.
Advancements in glaucoma management continue to evolve and this research opens avenues for refining surgical strategies, offering hope for improved outcomes and quality of life for glaucoma patients. The identification of these risk factors is a crucial step towards enhancing the effectiveness of Microshunt procedures, bringing us closer to more tailored and successful glaucoma interventions.
Source:
Rabiolo, A., Toscani, R., Sacchi, M., Destefanis, P., Bettin, P., Ciampi, C., Clemente, A., Cutolo, C. A., Mercieca, K., Iester, M., Traverso, C. E., Maita, M. D., Calzi, G. L., Nucci, P., Bandello, F., Triolo, G., & De Cillà , S. (2023). Risk factors for failure in glaucoma patients undergoing microshunt implantantion. American Journal of Ophthalmology. https://doi.org/10.1016/j.ajo.2023.11.011
Neuroscience Masters graduate
Jacinthlyn Sylvia, a Neuroscience Master's graduate from Chennai has worked extensively in deciphering the neurobiology of cognition and motor control in aging. She also has spread-out exposure to Neurosurgery from her Bachelor’s. She is currently involved in active Neuro-Oncology research. She is an upcoming neuroscientist with a fiery passion for writing. Her news cover at Medical Dialogues feature recent discoveries and updates from the healthcare and biomedical research fields. She can be reached at editorial@medicaldialogues.in
Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751