Medical Dialogues
  • Dermatology
Login Register
This site is intended for healthcare professionals only
Login Register
  • Medical Jobs
  • Medical Matrimony
  • MD Brand Connect
  • MDTV
    • Breaking News
    • Medical News Today
    • Health News Today
    • Latest
    • Journal Club
    • Medico Legal Update
    • Latest Webinars
    • MD Shorts
    • Health Dialogues
Medical Dialogues
  • Medical News & Guidelines
      • Anesthesiology
      • Cardiology and CTVS
      • Critical Care
      • Dentistry
      • Dermatology
      • Diabetes and Endocrinology
      • ENT
      • Gastroenterology
      • Medicine
      • Nephrology
      • Neurology
      • Obstretics-Gynaecology
      • Oncology
      • Ophthalmology
      • Orthopaedics
      • Pediatrics-Neonatology
      • Psychiatry
      • Pulmonology
      • Radiology
      • Surgery
      • Urology
      • Laboratory Medicine
      • Diet
      • Nursing
      • Paramedical
      • Physiotherapy
  • Health news
      • Doctor News
      • Government Policies
      • Hospital & Diagnostics
      • International Health News
      • MCI News
      • Medical Organization News
      • Medico Legal News
      • NBE News
      • NMC News
  • AYUSH
    • Ayurveda
    • Homeopathy
    • Siddha
    • Unani
    • Yoga
  • State News
      • Andaman and Nicobar Islands
      • Andhra Pradesh
      • Arunachal Pradesh
      • Assam
      • Bihar
      • Chandigarh
      • Chattisgarh
      • Dadra and Nagar Haveli
      • Daman and Diu
      • Delhi
      • Goa
      • Gujarat
      • Haryana
      • Himachal Pradesh
      • Jammu & Kashmir
      • Jharkhand
      • Karnataka
      • Kerala
      • Ladakh
      • Lakshadweep
      • Madhya Pradesh
      • Maharashtra
      • Manipur
      • Meghalaya
      • Mizoram
      • Nagaland
      • Odisha
      • Puducherry
      • Punjab
      • Rajasthan
      • Sikkim
      • Tamil Nadu
      • Telangana
      • Tripura
      • Uttar Pradesh
      • Uttrakhand
      • West Bengal
  • Medical Education
      • Ayush Education News
      • Dentistry Education News
      • Medical Admission News
      • Medical Colleges News
      • Medical Courses News
      • Medical Universities News
      • Nursing education News
      • Paramedical Education News
      • Study Aborad
  • Industry
      • Health Investment News
      • Health Startup News
      • Medical Devices News
      • Pharma News
      • Pharmacy Education News
      • Industry Perspective
  • MDTV
      • Health Dialogues MDTV
      • Health News today MDTV
      • Latest Videos MDTV
      • Latest Webinars MDTV
      • MD shorts MDTV
      • Medical News Today MDTV
      • Medico Legal Update MDTV
      • Top Videos MDTV
      • Health Perspectives MDTV
      • Journal Club MDTV
This site is intended for healthcare professionals only
LoginRegister
Medical Dialogues
LoginRegister
  • Home
  • Medical news & Guidelines
    • Anesthesiology
    • Cardiology and CTVS
    • Critical Care
    • Dentistry
    • Dermatology
    • Diabetes and Endocrinology
    • ENT
    • Gastroenterology
    • Medicine
    • Nephrology
    • Neurology
    • Obstretics-Gynaecology
    • Oncology
    • Ophthalmology
    • Orthopaedics
    • Pediatrics-Neonatology
    • Psychiatry
    • Pulmonology
    • Radiology
    • Surgery
    • Urology
    • Laboratory Medicine
    • Diet
    • Nursing
    • Paramedical
    • Physiotherapy
  • Health news
    • Doctor News
    • Government Policies
    • Hospital & Diagnostics
    • International Health News
    • MCI News
    • Medical Organization News
    • Medico Legal News
    • NBE News
    • NMC News
  • AYUSH
    • Ayurveda
      • Ayurveda Giuidelines
      • Ayurveda News
    • Homeopathy
      • Homeopathy Guidelines
      • Homeopathy News
    • Siddha
      • Siddha Guidelines
      • Siddha News
    • Unani
      • Unani Guidelines
      • Unani News
    • Yoga
      • Yoga Guidelines
      • Yoga News
  • State News
    • Andaman and Nicobar Islands
    • Andhra Pradesh
    • Arunachal Pradesh
    • Assam
    • Bihar
    • Chandigarh
    • Chattisgarh
    • Dadra and Nagar Haveli
    • Daman and Diu
    • Delhi
    • Goa
    • Gujarat
    • Haryana
    • Himachal Pradesh
    • Jammu & Kashmir
    • Jharkhand
    • Karnataka
    • Kerala
    • Ladakh
    • Lakshadweep
    • Madhya Pradesh
    • Maharashtra
    • Manipur
    • Meghalaya
    • Mizoram
    • Nagaland
    • Odisha
    • Puducherry
    • Punjab
    • Rajasthan
    • Sikkim
    • Tamil Nadu
    • Telangana
    • Tripura
    • Uttar Pradesh
    • Uttrakhand
    • West Bengal
  • Medical Education
    • Ayush Education News
    • Dentistry Education News
    • Medical Admission News
    • Medical Colleges News
    • Medical Courses News
    • Medical Universities News
    • Nursing education News
    • Paramedical Education News
    • Study Aborad
  • Industry
    • Health Investment News
    • Health Startup News
    • Medical Devices News
    • Pharma News
      • CDSCO (Central Drugs Standard Control Organisation) News
    • Pharmacy Education News
    • Industry Perspective
  • Home
  • Orthopaedics
  • Orthopaedics News
  • Higher fasting blood...

Higher fasting blood sugar worsens knee symptoms in patients with knee osteoarthritis

Medha BaranwalWritten by Medha Baranwal Published On 2023-01-03T20:00:15+05:30  |  Updated On 3 Jan 2023 2:30 PM GMT
Higher fasting blood sugar worsens knee symptoms in patients with knee osteoarthritis
  • facebook
  • twitter
  • linkedin
  • whatsapp
  • Telegram
  • koo
  • Email

Japan: A recent study in Arthritis Research & Therapy has shown that higher blood sugar levels in patients with radiographic knee osteoarthritis (KOA) and central sensitization (CS) are associated with worsened knee symptoms during the 1-year follow-up.The authors suggest healthcare providers pay attention to controlling blood sugar, specifically in patients with knee osteoarthritis...

Japan: A recent study in Arthritis Research & Therapy has shown that higher blood sugar levels in patients with radiographic knee osteoarthritis (KOA) and central sensitization (CS) are associated with worsened knee symptoms during the 1-year follow-up.

The authors suggest healthcare providers pay attention to controlling blood sugar, specifically in patients with knee osteoarthritis and concurrent central sensitization to reduce their knee symptoms.

Cross-sectional and cohort data have suggested that higher serum blood glucose levels in patients with KOA are linked with more severe knee symptoms; more is needed about the longitudinal relationship between serum blood sugar and knee symptoms, especially considering CS comorbidity, which also deteriorates knee symptoms.

Against the above background, Daisuke Chiba from Hirosaki University Graduate School of Medicine in Aomori, Japan, and colleagues aimed to assess the longitudinal relationship between fasting blood sugar (FBG) at baseline and change in knee symptoms based on central sensitization comorbidity. They hypothesized that a higher FBG level is more likely to cause a decline in knee symptoms in patients with knee osteoarthritis and comorbid CS.

The authors enrolled 297 participants (mean age: 59.6 years) in the study. At baseline, the evaluation of plain radiographs of the bilateral knee joints was done according to the Kellgren–Lawrence grade (KLG). All patients showed at least a KLG ≥ 2 in each knee. Fasting blood sugar and Central Sensitization Inventory-9 (CSI-9) were assessed at baseline; more than 10 points on the CSI-9 were defined as CS+. KOOS (Knee injury and Osteoarthritis Outcome Score) was investigated at baseline and a follow-up of 1 year; ΔKOOS (change in KOOS) was calculated by subtracting the KOOS at baseline from KOOS at the follow-up of 1 year. ΔKOOS was taken as the dependent variable, and the independent variable was FBG after adjustments for sex, age, CSI-9, and BMI at baseline.

The key findings of the study were:

· Of the 297 subjects, 16.2 % were defined as CS+. In the CS − group, no association was found between FBG levels at baseline and ΔKOOS.

· FBG at baseline was negatively linked with ΔKOOS pain (B = − 0.448), ADL (B = − 0.438), and sports (B = − 0.706).

To sum up, higher FBG levels at the baseline deteriorated knee symptoms in radiographic knee osteoarthritis and comorbid CS patients during a follow-up of 1 year. On the other hand, fasting blood sugar was not longitudinally associated with knee symptoms.

"There was a negative association between CS comorbidity and KOOS scores at baseline for patients with radiographic KOA. However, CS itself did not impact longitudinal changes in KOOS," the authors wrote. "Therefore, comorbid CS deteriorated knee symptoms in radiographic KOA patients only when their fasting blood sugar was increased."

Reference:

Chiba, D., Ohyama, T., Sasaki, E. et al. Higher fasting blood glucose worsens knee symptoms in patients with radiographic knee osteoarthritis and comorbid central sensitization: an Iwaki cohort study. Arthritis Res Ther 24, 269 (2022).

https://doi.org/10.1186/s13075-022-02951-2



Arthritis Research & Therapyknee osteoarthritiscentral sensitizationfasting blood glucosehyperglycemiaBlood sugar
Source : Arthritis Research & Therapy
Medha Baranwal
Medha Baranwal

    MSc. Biotechnology

    Medha Baranwal joined Medical Dialogues as an Editor in 2018 for Speciality Medical Dialogues. She covers several medical specialties including Cardiac Sciences, Dentistry, Diabetes and Endo, Diagnostics, ENT, Gastroenterology, Neurosciences, and Radiology. She has completed her Bachelors in Biomedical Sciences from DU and then pursued Masters in Biotechnology from Amity University. She has a working experience of 5 years in the field of medical research writing, scientific writing, content writing, and content management. She can be contacted at  editorial@medicaldialogues.in. Contact no. 011-43720751

    Show Full Article
    Next Story
    Similar Posts
    NO DATA FOUND

    Editorial

    Journal Club Today

    Health News Today

    © 2022 All Rights Reserved.
    Powered By: Hocalwire
    X
    X