Low muscle mass linked to higher risk of hip fracture;BMC
Sarcopenia,age related muscle loss, has been identified as a risk factor for falls among older individuals, while patients with sarcopenia suffer from increased incidences of fractures . Indeed, previous reports have noted that sarcopenia was a risk factor for hip fracture, which also affect activities of daily living and mortality among older individuals. Another study had previously found that half of the patients with hip fracture ultimately develop permanent disability and mobility and are at high risk of institutionalization.
According to new study findings,Patients with hip fracture who had low muscle mass had a lower Barthel index, lower home discharge rate, and higher one-year mortality, indicating that low muscle mass to be a risk factor for one-year mortality among those with hip fracture. The findings have been put forth in BMC Musculoskeletal Disorders .
Although sarcopenia has been known as a risk factor for hip fracture, only a few reports have described the impact of muscle mass on hip fracture treatment outcomes.
To gain a greater insight into this topic, the current study aimed to investigate the impact of muscle mass on hip fracture treatment outcomes.
In the study design, this case–control study involved 337 patients (67 males and 270 females) with hip fracture aged ≥65 years (mean age: 84.1 ± 7.1 years) who underwent orthopedic surgery from January 2013 to June 2019. The mean follow-up period was 17.1 (1–60) months. Upon admission, all patients were assessed for low muscle mass according to the Asian Working Group for Sarcopenia criteria (male, SMI < 7.00 kg/m2; female, SMI < 5.40 kg/m2) using dual-energy X-ray absorptiometry. Treatment outcomes (stays at acute care institutions, hospital mortality, the Barthel index at discharge, and home discharge rates, and one-year mortality) were compared between patients with and without low muscle mass by Student's t-test, Mann-Whitney U test and the Pearson Chi-Square test.
Furthermore, researchers determined whether low muscle mass was a risk factor for one-year mortality in hip fracture patients using a Cox proportional hazards model.
Data analysis revealed some interesting facts.
- The prevalence of low muscle mass in patients with hip fracture was 231(68.5%).
- Those with low muscle mass had a lower Barthel index (P < 0.0001), hospital discharge rate (P = 0.035) and higher one-year mortality (P = 0.010).
- Cox proportional hazards regression analysis adjusted for age and sex found that low muscle mass was a risk factor for one-year mortality (hazard ratio, 3.182, 95% confidence interval, 1.097–9.226, P = 0.033).
For the full article follow the link: https://doi.org/10.1186/s12891-021-04143-6