Ano-Metrogyl

About ANO- metrogyl

Ano Metrogyl is a Cream used in the treatment of the treatment of bedsore, hemorrhoids, fistulae and anal fissures.

Ano metrogyl is composed of Lidocaine, Metronidazole and Sucralfate.

Indications of ANO-metrogyl

• It is indicated for the treatment of bedsore, hemorrhoids, fistulae and anal fissures.

Direction for Use

Route of Administration: Topical Clean the affected area with mild soap and warm water. Rinse thoroughly and pat dry, Apply the cream with the special applicator. Cleanse the applicatory thoroughly after use. Keep the product out of Children’s reach.

Contraindications

ANO-metrogyl is contraindicated in patients with a history of hypersensitivity to metronidazole, amide-type local anesthetics, sucralfate or to any other ingredient in the formulation. Caution is recommended in lactating females.

ANO-metrogyl Cream should not be used during pregnancy unless considered essential by the physician. (Download the Product Leaflet, for more details.)

Warnings and Precautions

Avoid contact with eyes. If eye contact occurs, immediately wash out the eye with water or saline and protect the eye until sensation returns.

Do not apply to irritated skin or if excessive irritation develops. Dermal application may cause transient local blanching followed by transient erythema.

Download the Product Leaflet, to see the detailed warnings and precautions.

Drug Interactions

Drug interactions should be kept in mind when ANO-metrogyl cream is prescribed for patients who are receiving anticoagulant treatment, although they are less likely to occur with topical administration because of low absorption. ANO-metrogyl cream should be used with caution in patients receiving Class I anti-arrhythmic drugs (such as tocainide and mexiletine) since the toxic effects are additive and generally synergistic.

Download the Product Leaflet, to see the detailed drug interactions

Undesirable Side effects/ Overdose

Common (>1/100 to <1/10), Uncommon (>1/1,000 to <1/100), Rare (>1/10,000 to <1/1,000), Very rare (< 1/10,000), Not known (cannot be estimated from available data).

Skin and subcutaneous tissue disorders:
Common-Dry skin, erythema, pruritus, skin discomfort (burning, pain of skin/stinging), skin irritation, redness, itching, rash, urticaria worsening of rosacea. Unknown frequency- Contact dermatitis, swelling face, skin exfoliation.

Nervous system disorders:
Uncommon- Hypothesia, paraesthesia, dysgeusia (metallic taste).

Gastrointestinal disorders:
Uncommon-Nausea.
In rare cases local anesthetics have been associated with allergic reactions including anaphylactic shock. Corneal irritation after accidental eye exposure.

Download the Product Leafletto see the detailed information on the Undesirable Side effects/ Overdose

Pharmacodynamic and Pharmacokinetic Properties

Download the Product Leaflet, to see the details on Pharmacodynamic and Pharmacokinetic Properties

Journal update

• Systematic review and meta-analysis of the role of metronidazole in post-haemorrhoidectomy pain relief

• Topical Sucralfate Treatment of Anal Fistulotomy Wounds: A Randomized Placebo-Controlled Trial

• Efficacy of combination of 0.2% GTN and lignocaine ointments in wound healing and pain relief after Milligan Morgan hemorrhoidectomy – A comparison with lignocaine and 0.2% GTN ointments separately