Bizfer XT is a Fixed Dose Combination of Ferrous Bis-glycinate, Folic acid IP, Zinc, Bis-glycinate, and Methylcobalamin USP. It is marketed by J.B. Chemicals & Pharmaceuticals Ltd.
Bizfer XT is used for the treatment of vitamin deficiency states in adults.
Ferrous Bis-glycinate is a chelated form of iron. Zinc acts as a cofactor for more than 70 different enzymes. Zinc dependent enzymes are involved in the metabolism of carbohydrates, lipids, and proteins. Zinc facilitates wound healing, normal growth rates, normal skin hydration and maintains senses of taste and smell. It provides normal growth and tissue repair. It also helps in development of cell mediated immunity.
Folic acid reduced by enzymes folate reductase and dihydrofolate reductase and forms dihydrofolic acid tetrahydrofolic acid respectively. Tetrahydrofolic acid acts as a coenzyme which mediates a number of one carbon transfer reactions by carrying a methyl group as an adduct. Folic acid is required to maintain normal erythropoiesis and nucleoprotein synthesis.
Vitamin B12 (Methylcobalamin )is an essential constituent for growth, cell reproduction, hematopoiesis, and nucleoprotein and myelin synthesis. Vitamin B12 is converted in to coenzyme B12 in the tissues which is essential for conversion of methyl-malonate to succinate and synthesis of methionine from homocystine. It is also associated with fat and carbohydrate metabolism and protein synthesis. Cells characterized by rapid division such as epithelial cells, bone marrow, and myeloid cells appear to have greatest requirement of Cyanocobalamin.