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Ferrous-Bis-glycinate-Bizfer XT

Bizfer XT is a Fixed Dose Combination of Ferrous Bis-glycinate, Folic acid IP, Zinc, Bis-glycinate, and Methylcobalamin USP. It is marketed by J.B. Chemicals & Pharmaceuticals Ltd.


Bizfer XT is used for the treatment of vitamin deficiency states in adults.


Ferrous Bis-glycinate is a chelated form of iron. Zinc acts as a cofactor for more than 70 different enzymes. Zinc dependent enzymes are involved in the metabolism of carbohydrates, lipids, and proteins. Zinc facilitates wound healing, normal growth rates, normal skin hydration and maintains senses of taste and smell. It provides normal growth and tissue repair. It also helps in development of cell mediated immunity.


Folic acid reduced by enzymes folate reductase and dihydrofolate reductase and forms dihydrofolic acid tetrahydrofolic acid respectively. Tetrahydrofolic acid acts as a coenzyme which mediates a number of one carbon transfer reactions by carrying a methyl group as an adduct. Folic acid is required to maintain normal erythropoiesis and nucleoprotein synthesis.


Vitamin B12 (Methylcobalamin )is an essential constituent for growth, cell reproduction, hematopoiesis, and nucleoprotein and myelin synthesis. Vitamin B12 is converted in to coenzyme B12 in the tissues which is essential for conversion of methyl-malonate to succinate and synthesis of methionine from homocystine. It is also associated with fat and carbohydrate metabolism and protein synthesis. Cells characterized by rapid division such as epithelial cells, bone marrow, and myeloid cells appear to have greatest requirement of Cyanocobalamin.

Overview
Name of Product: BIZFER XT Tablets
Marketed by : J.B. Chemicals & Pharmaceuticals Ltd.
Medicine composition: Each film coated tablet of BIZFER XT Tablet contains:
Ferrous Bis-glycinate
Equivalent to Elemental Iron.................................60 mg.
Folic Acid IP .............................................................1mg
Zinc Bis-glycinate
Equivalent to Elemental Zinc................................15 mg.
Methylcobalamin IP...........................................500 mcg.
Excipients...................................................................Q.S.
Colour: Lake of Erythrocine & Sunset yellow
Prescription vs.OTC: Prescription by Doctor required
Dosage Form: Film coated tablets

BIZFER XT is a Fixed Dose Combination of Ferrous Bis-glycinate, Folic acid IP, Zinc Bis-glycinate, and Methylcobalamin USP. It is used for the treatment of vitamin deficiency states in adults.

The recommended adult oral dosage of Bizfer XT (FDC of Ferrous Bis-glycinate, Folic acid IP, Zinc Bis-glycinate, and Methylcobalamin USP) is one tablet .
Please download the complete Product Leaflet to see the details on Dosage of Bifzer XT .

FDC of Ferrous Bis-glycinate, Folic acid IP, Zinc Bis-glycinate, and Methylcobalamin USP is contraindicated in.

  • Patients sensitive to Ferrous Bis-glycinate, Folic acid IP, Zinc Bis-glycinate, and Methylcobalamin USP or to any of the excipients of the product.
  • Hypersensitivity to the drug.
  • Leber’s disease.

Download Leaflet for details on Contraindications.

Zinc

  • Don’t exceed prescribed dose.
  • Renal failure.
  • Biliary obstruction.

Folic acid

  • In patients with undiagnosed anaemia; because it may mask pernicious anaemia.
  • In pernicious anaemia and other megaloblastic where vitamin B12 is deficient.

Vitamin B12 (Methylcobalamin)

  • InAnemic patients with coexisting cardiac, pulmonary and hypertensive disease.
  • Download Leaflet to see the detailed warnings and precautions.

Download the Product Leaflet, to see the details on Pharmacodynamic and Pharmacokinetic Properties of Bizfer XT

Contact us for further information

Bizfer XT is a Fixed Dose Combination of Ferrous Bis-glycinate, Folic acid IP, Zinc, Bis-glycinate, and Methylcobalamin USP. It is marketed by J.B. Chemicals & Pharmaceuticals Ltd.


Bizfer XT is used for the treatment of vitamin deficiency states in adults.


Ferrous Bis-glycinate is a chelated form of iron. Zinc acts as a cofactor for more than 70 different enzymes. Zinc dependent enzymes are involved in the metabolism of carbohydrates, lipids, and proteins. Zinc facilitates wound healing, normal growth rates, normal skin hydration and maintains senses of taste and smell. It provides normal growth and tissue repair. It also helps in development of cell mediated immunity.


Folic acid reduced by enzymes folate reductase and dihydrofolate reductase and forms dihydrofolic acid tetrahydrofolic acid respectively. Tetrahydrofolic acid acts as a coenzyme which mediates a number of one carbon transfer reactions by carrying a methyl group as an adduct. Folic acid is required to maintain normal erythropoiesis and nucleoprotein synthesis.


Vitamin B12 (Methylcobalamin )is an essential constituent for growth, cell reproduction, hematopoiesis, and nucleoprotein and myelin synthesis. Vitamin B12 is converted in to coenzyme B12 in the tissues which is essential for conversion of methyl-malonate to succinate and synthesis of methionine from homocystine. It is also associated with fat and carbohydrate metabolism and protein synthesis. Cells characterized by rapid division such as epithelial cells, bone marrow, and myeloid cells appear to have greatest requirement of Cyanocobalamin.

Drug Interactions


Zinc

  • Fluoroquinolone, Tetracycline: Decreased GI absorption and serum levels of some fluoroquinolone
  • Pencillamine: Reduced absorption of zinc.
  • Iron: Reduced absorption of iron and vice versa.

Folic acid

  • Hypersensitivity reactions with injection form.
  • Bronchospasm.

Download the Product Leaflet, to see the detailed drug interactions.

ferrous bis-glycinate side effects/Overdose


Zinc


Nausea, vomiting, abdominal distress, Gastric ulceration, and Rashes.

Vitamin B12 (Methylcobalamin)


Anaphylaxis, Anaphylactoid reactions, pain and burning sensation at injection site, itching, urticaria, transient diarrhea, peripheral vascular thrombosis, and pulmonary oedema.
If you notice other side-effects not listed above, contact your doctor for medical advice. You may also report side-effects to your local food and drug administration authority.

Download the Product Leaflet, to see the the detailed information on the ferrous bis-glycinate side effects/Overdose.