Myotan (Azilsartan Medoxomil Tablet) is a angiotensin II receptor blocker (ARB) used in the therapy of hypertension. Myotan is marketed by J.B. Chemicals & Pharmaceuticals Ltd. and comes in two doses namely Myotan 40 mg and Myotan 80 mg.
Azilsartan inhibits the pressor effects of an angiotensin II infusion in a dose-related manner. Azilsartan blocks the vasoconstrictor and aldosterone secreting effects of angiotensin II by selectively blocking the binding of angiotensin II to the AT1 receptor in many tissues, such as vascular smooth muscle and the adrenal gland. Its action is, therefore, independent of the pathway for angiotensin II synthesis
Azilsartan is a highly selective AT1 subtype angiotensin II receptor antagonist. Azilsartan blocks the vasoconstrictor and aldosterone-secreting effects of angiotensin II by selectively blocking the binding of angiotensin II to the AT1 receptor in many tissues, such as vascular smooth muscle and the adrenal gland. This action relaxes blood vessels and reduces high blood pressure..
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