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  • Maternal influenza...

Maternal influenza vaccination during pregnancy may protect infant in first few months of life: JAMA

Written By : Dr Riya Dave |Medically Reviewed By : Dr. Kamal Kant Kohli Published On 2023-12-19T23:30:42+05:30  |  Updated On 12 Feb 2024 11:55 PM IST
Maternal influenza vaccination during pregnancy may protect infant in first few months of life: JAMA
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A recent study exploring the impact of maternal influenza vaccination during pregnancy has shown promising outcomes in reducing influenza-related hospitalizations and emergency department (ED) visits in infants under 6 months of age. The study, conducted using data from the New Vaccine Surveillance Network across multiple influenza seasons, sheds light on the protective benefits of maternal vaccination against influenza-associated illnesses in young infants.

The study was published in the journal of JAMA Pediatrics by Leila Sahni and colleagues. The study included 3764 infants, among whom 53% were born to mothers who received influenza vaccination during pregnancy. The overall effectiveness of maternal vaccination in infants against influenza-related hospitalizations and ED visits was estimated at 34%. Specifically, the vaccine demonstrated a 39% effectiveness in preventing hospitalizations and a 19% effectiveness in mitigating ED visits associated with influenza.

Among infants younger than 3 months, the effectiveness of maternal vaccination soared to 53%, indicating a stronger protective effect in this vulnerable age group. Notably, infants born to mothers vaccinated during the third trimester exhibited a higher effectiveness rate of 52%, whereas those whose mothers were vaccinated during the first or second trimesters showed a lower effectiveness rate of 17%.

The study's findings underscore the significance of maternal influenza vaccination during pregnancy in reducing the risk of influenza-associated hospitalizations and ED visits in infants below 6 months of age. The observed effectiveness was particularly notable in younger infants and those born to mothers vaccinated during the later stages of pregnancy.

These results emphasize the importance of promoting maternal influenza vaccination as a crucial preventive measure to safeguard both maternal and infant health. Encouraging vaccination, especially during the third trimester, could offer substantial protection against influenza-related complications in vulnerable newborns.

Reference:

Sahni, L. C., Olson, S. M., Halasa, N. B., Stewart, L. S., Michaels, M. G., Williams, J. V., Englund, J. A., Klein, E. J., Staat, M. A., Schlaudecker, E. P., Selvarangan, R., Schuster, J. E., Weinberg, G. A., Szilagyi, P. G., Boom, J. A., Patel, M. M., Muñoz, F. M., McNeal, M., Rohlfs, C., … New Vaccine Surveillance Network Collaborators. Maternal vaccine effectiveness against influenza-associated hospitalizations and emergency department visits in infants. JAMA Pediatrics,2023. https://doi.org/10.1001/jamapediatrics.2023.5639

JAMA PediatricsMaternal Influenza VaccinationInfluenza-associated HospitalizationsNew Vaccine Surveillance NetworkInfluenza PreventionPediatric HealthPregnancyInfant Health
Source : JAMA Pediatrics
Dr Riya Dave
Dr Riya Dave

    Dr Riya Dave has completed dentistry from Gujarat University in 2022. She is a dentist and accomplished medical and scientific writer known for her commitment to bridging the gap between clinical expertise and accessible healthcare information. She has been actively involved in writing blogs related to health and wellness.

    Dr. Kamal Kant Kohli
    Dr. Kamal Kant Kohli

    Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751

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