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  • Phthalate exposure...

Phthalate exposure during pregnancy tied with increased risk for preterm birth: JAMA

Written By : Dr. Shravani Dali |Medically Reviewed By : Dr. Kamal Kant Kohli Published On 2022-08-16T09:15:25+05:30  |  Updated On 16 Aug 2022 2:32 PM IST
Phthalate exposure during pregnancy tied with increased risk for preterm birth: JAMA
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Exposure to phthalates increases the risk of preterm birth, according to a recent study published in JAMA Pediatrics.

According to a new study by the National Institutes of Health, pregnant women who were exposed to multiple phthalates during pregnancy were at increased risk of preterm birth. Phthalate esters are chemicals used in personal care products such as cosmetics, as well as solvents, detergents, and food packaging.

Analyzing data from more than 6,000 pregnant women in the United States, researchers found that women with high levels of certain phthalate metabolites in their urine were more than three weeks before their mother's expected due date. I found out that there is a high chance of premature delivery.

In the most extensive study in this area, Ferguson and his team pooled data from 16 studies conducted across the United States. This includes prenatal (representative of phthalate exposure) and delivery of urinary phthalate metabolites. Researchers analyzed data from 6,045 pregnant women who gave birth between 1983 and 2018. Nine per cent of the women who participated in this study, or 539 people, had a preterm birth. Phthalate metabolites were detected in more than 96% of urine samples.

The higher the concentration of the investigated phthalate metabolites, the higher the probability of preterm delivery. Exposure to 4 of 11 phthalates in pregnant women was associated with a 14 to 16 per cent increased risk of preterm birth. The most consistent findings are for exposure to phthalates, which are commonly used in personal care products such as nail polish and cosmetics.

The researchers also used statistical models to simulate interventions that would reduce exposure to phthalates.

Thus, the researchers found that reducing phthalate metabolite levels by 50% could prevent feathering.

Reference:

Welch BM, et al. JAMA Pediatr. 2022;doi:10.1001/jamapediatrics.2022.2252



phthalateincreased riskpreterm birthjama pediatrics
Source : JAMA Pediatrics
Dr. Shravani Dali
Dr. Shravani Dali

    Dr. Shravani Dali has completed her BDS from Pravara institute of medical sciences, loni. Following which she extensively worked in the healthcare sector for 2+ years. She has been actively involved in writing blogs in field of health and wellness. Currently she is pursuing her Masters of public health-health administration from Tata institute of social sciences. She can be contacted at editorial@medicaldialogues.in.

    Dr. Kamal Kant Kohli
    Dr. Kamal Kant Kohli

    Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751

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