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Vitamin D deficiency associated with UTI in children: Study
The incidence of urinary tract infection is more commonly seen in children with vitamin D deficiency, suggests a study published in Pakistan Journal of Medical Sciences.
A study was conducted by a group of researchers from Pakistan to demonstrate the Vitamin-D levels in children with urinary tract infection.
The researchers undertook a cross-sectional study at Pediatric Department, Liaquat University Hospital Hyderabad, Pakistan from July 2019 to March 2020.
The selected a total of 172 children of both genders ranging from 2 to 60 months of age with a confirmed diagnosis of urinary tract infection (UTI) for this study. There were 130 (75.58%) females and 40 (23.25%) males. The kids who received antibiotics 48 hours before or already on immunosuppressive drugs and steroids from previous health records or by taking clinically relevant history), children with CKD on vitamin-D supplementation, and known case of Vitamin-D deficiency were also excluded from the study.
All the participants were assessed for vitamin D level by high-performance liquid chromatography. The urine sample was collected for C/S and 1 cc venous blood was taken for Vitamin D level (ng/ml).
The mean ± standard deviation (SD) and stratification was calculated for age, duration of urinary tract infection, and vitamin-D level. Post-stratification chi-square test was also applied for all categorical variables at 95% confidence interval (CI) and P-value ≤0.05 was considered significant.
The findings of the study are as follows:
· 87.21% of children had a complaint of fever, followed by vomiting in 18.02,
· abdominal pain in 12.79% and dysuria in 8.72% of children.
· A total of 129 (75%) children had pyelonephritis and 15 (25%) had cystitis.
· Mild vitamin D deficiency was present in 42 (53.16%) children, while moderate deficiency in 55 (69.62%) children. E. Coli was the most common pathogen in both mild and moderate vitamin D deficiency i.e., 20 (47.61) and 31 (56.36%) respectively.
The researchers concluded that the frequency of urinary tract infection is more common in children having vitamin D deficiency.
Reference:
Frequency of Vitamin-D deficiency in children with Urinary tract infection: A descriptive a cross-sectional study by Qadir S published in the Pakistan Journal of Medical Sciences.
DOI: 10.12669/pjms.37.4.3896
Dr. Shravani Dali has completed her BDS from Pravara institute of medical sciences, loni. Following which she extensively worked in the healthcare sector for 2+ years. She has been actively involved in writing blogs in field of health and wellness. Currently she is pursuing her Masters of public health-health administration from Tata institute of social sciences. She can be contacted at editorial@medicaldialogues.in.
Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751