Therapeutic Potential of Ibuprofen-Paracetamol Combination for Use in Children
Children suffer frequent episodes of illness leading to more primary care visits as compared to any other age group.(1) It is getting emphasized that, for febrile children without any indication of a serious underlying condition, there is a need to treat symptoms of fever along with a focus on comforting the child, rather than only achieving normothermia .(2) This implies the need to relieve the clinical inflammatory state i.e. the pain which is often associated with fever (2)
Paracetamol and ibuprofen are the most widely prescribed medications for the management of fever and pain in children.(3) Ibuprofen is cited as the most studied nonsteroidal anti-inflammatory drug in the management of pain associated with inflammation in children; with durable evidence of efficacy and a good safety profile (4). The clinical utility and therapeutic potential of Ibuprofen plus Paracetamol combination treatment in routine practice settings is reviewed through comprehensive and recently available scientific evidence.