Adherence to MIND diet may lower risk of incident dementia in middle-aged and older adults: JAMA

Written By : Jacinthlyn Sylvia |Medically Reviewed By : Dr. Kamal Kant Kohli Published On 2023-05-10T09:15:49+05:30 | Updated On 10 May 2023 2:59 PM IST

In middle-aged and older adults, following MIND diet was linked to a lower risk of incident dementia, says an article published in the Journal of American Medical Association Psychiatry.

Older persons' wellbeing is threatened by dementia, thus preventative measures are crucial. In order to assess the relationship between the Mediterranean-Dietary Approaches to Stop Hypertension (DASH) Intervention for Neurodegenerative Delay (MIND) diet and the risk of dementia in 3 prospective trials and a meta-analysis, Hui Chen and colleagues undertook this investigation.

The meta-analysis includes 11 cohort studies, including the Whitehall II study (WII), the Health and Retirement Study (HRS), and the Framingham Heart Study Offspring group (FOS). Women and men in their middle and later years without dementia who participated in the study were recruited from the WII in 2002 to 2004, HRS in 2013, and FOS in 1998 to 2001. From May 25 through September 1, 2022, data were examined. Food frequency surveys were used to determine the MIND diet score, which varied from 0 to 15, with a higher score suggesting more adherence to the MIND diet. Incident all-cause dementia with cohort-specific criteria is the study's key finding.

The key findings of this study were:

1. 8358 people from WII, 6758 participants from HRS, and 3020 participants from FOS were included in this study.

2. The mean (SD) baseline MIND diet score for WII, HRS, and FOS was 8.3 (1.4), 7.1 (1.9), and 8.1 (1.6), respectively.

3. A total of 775 individuals experienced incident dementia over 166 516 person-years.

4. A higher MIND diet score was linked to a decreased risk of dementia in the multivariable-adjusted Cox proportional hazard model.

5. In subgroups based on age, sex, smoking status, and body mass index, the relationships were consistently seen.

6. The greatest tertile of MIND diet score was related to decreased risk of dementia compared with the lowest tertile in the meta-analysis of 11 cohort studies involving 224 049 individuals.

Reference:

Chen, H., Dhana, K., Huang, Y., Huang, L., Tao, Y., Liu, X., Melo van Lent, D., Zheng, Y., Ascherio, A., Willett, W., & Yuan, C. (2023). Association of the Mediterranean Dietary Approaches to Stop Hypertension Intervention for Neurodegenerative Delay (MIND) Diet With the Risk of Dementia. In JAMA Psychiatry. American Medical Association (AMA). https://doi.org/10.1001/jamapsychiatry.2023.0800

JAMA PsychiatryMediterranean dietDASHdementia risk

Source : JAMA Psychiatry

Jacinthlyn Sylvia

Neuroscience Masters graduate

Jacinthlyn Sylvia, a Neuroscience Master's graduate from Chennai has worked extensively in deciphering the neurobiology of cognition and motor control in aging. She also has spread-out exposure to Neurosurgery from her Bachelor’s. She is currently involved in active Neuro-Oncology research. She is an upcoming neuroscientist with a fiery passion for writing. Her news cover at Medical Dialogues feature recent discoveries and updates from the healthcare and biomedical research fields. She can be reached at editorial@medicaldialogues.in

Dr. Kamal Kant Kohli

Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751