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Early Desaturation During 6-Minute Walk Test Predictor of Mortality in COPD
![Early Desaturation During 6-Minute Walk Test Predictor of Mortality in COPD Early Desaturation During 6-Minute Walk Test Predictor of Mortality in COPD](https://medicaldialogues.in/h-upload/2023/04/24/750x450_208139-4082023613fig3html.webp)
Early Desaturation During 6-Minute Walk Test is a Predictor of Mortality in COPD suggests a new study published in the Lung
Oxygen desaturation during exercise is mainly observed in severe cases of chronic obstructive pulmonary disease (COPD) and is associated with a worse prognosis, but little is known about the type of desaturation that causes the greatest risk of mortality.
The researchers studied all of the 6-min walk tests performed periodically at a tertiary hospital over a period of 12 years in patients with moderate or severe COPD. We classified patients as non-desaturators if they did not suffer a drop in oxygen saturation (SpO2 < 88%) during the test, early desaturators if the time until desaturation was < 1 min, and non-early desaturators if it was longer than 1 min. The average length of follow-up per patient was 5.6 years.
Results:
Of the 319 patients analyzed, 126 non-desaturators, 91 non-early desaturators and 102 early desaturators were identified. The mortality analysis showed that early desaturators had a mortality of 73%, while it was 38% for non-early desaturators and 28% for non-desaturators, with a survival of 5.9 years compared to 7.5 years and 9.6 years, respectively
The early desaturation seen in patients with chronic obstructive pulmonary disease is associated with greater mortality and is likely responsible for the poor prognosis shown globally in patients who desaturate. The survival of patients with early desaturation is almost 4 years less with respect to non-desaturators, and they, thus, require closer observation.
Reference:
García-Talavera I, Figueira-Gonçalves JM, Golpe R, Esteban C, Amado C, Pérez-Méndez LI, Aramburu A, Conde-Martel A. Early Desaturation During 6-Minute Walk Test is a Predictor of Mortality in COPD. Lung. 2023 Apr;201(2):217-224. doi: 10.1007/s00408-023-00613-x. Epub 2023 Apr 10. PMID: 37036523.
Keywords:
Early, Desaturation, During, 6-Minute, Walk Test, Predictor, Mortality, COPD, García-Talavera I, Figueira-Gonçalves JM, Golpe R, Esteban C, Amado C, Pérez-Méndez LI, Aramburu A, Conde-Martel, Lung
Dr. Shravani Dali has completed her BDS from Pravara institute of medical sciences, loni. Following which she extensively worked in the healthcare sector for 2+ years. She has been actively involved in writing blogs in field of health and wellness. Currently she is pursuing her Masters of public health-health administration from Tata institute of social sciences. She can be contacted at editorial@medicaldialogues.in.
Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: editorial@medicaldialogues.in. Contact no. 011-43720751