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  • Risk-based lung cancer...

Risk-based lung cancer screening more cost-effective than age, smoking history-based screening

Dr. Kamal Kant KohliWritten by Dr. Kamal Kant Kohli Published On 2023-02-09T20:00:49+05:30  |  Updated On 9 Feb 2023 2:30 PM GMT
Risk-based lung cancer screening more cost-effective than age, smoking history-based screening
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An analysis of lung cancer screening methods found that risk-based lung cancer screening was more cost-effective than age and smoking history-based screening methods. The analysis is published in the Annals of Internal Medicine. In 2021, the U.S. Preventive Services Task Force (USPSTF) issued their updated recommendation on lung cancer screening that lowers the starting age from 55 to 50...

An analysis of lung cancer screening methods found that risk-based lung cancer screening was more cost-effective than age and smoking history-based screening methods. The analysis is published in the Annals of Internal Medicine.

In 2021, the U.S. Preventive Services Task Force (USPSTF) issued their updated recommendation on lung cancer screening that lowers the starting age from 55 to 50 years and the minimum cumulative smoking exposure from 30 to 20 pack-years (categorical age-smoking strategies). However, prior studies suggest that risk-based lung cancer screening that defines screening eligibility based on personal lung cancer risk scores using validated prediction models averts more lung cancer deaths and results in fewer radiation-related deaths than categorical age-smoking strategies.

A team of researchers for the National Cancer Institute (NCI)-sponsored consortium, Cancer Intervention and Surveillance Modelling Network (CISNET) Lung Group used data from the National Lung Screening Trial to evaluate and compare the cost-effectiveness of risk model–based lung cancer screening strategies versus the USPSTF recommendation and to explore optimal risk thresholds.

The CISNET Lung group previously helped the decision-making of USPSTF on their recommendation on the national lung cancer screening guidelines in 2013 and 2021 through a comparative modeling approach used in this study. The data showed that risk-based screening was associated with more quality-adjusted life-years (QALY) and cost-savings compared with categorical age-smoking strategies. The authors note that risk model–based screening strategies were consistently more cost-effective than the 2021 USPSTF recommendation under varying modeling assumptions, including when a minimum 5-year life expectancy was included as an eligibility criterion and when imperfect adherence was implemented.

Reference:

https://www.acpjournals.org/doi/10.7326/M22-2216

Annals of Internal Medicinelung cancerlung cancer screeningcancersmoking history-based screening
Source : Annals of Internal Medicine
Dr. Kamal Kant Kohli
Dr. Kamal Kant Kohli

    Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Before Joining Medical Dialogues, he has served at important positions in the medical industry in India including as the Hony. Secretary of the Delhi Medical Association as well as the chairman of Anti-Quackery Committee in Delhi and worked with other Medical Councils in India. Email: editorial@medicaldialogues.in. Contact no. 011-43720751

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