Medical Dialogues
  • Dermatology
Login Register
This site is intended for healthcare professionals only
Login Register
  • Medical Jobs
  • Medical Matrimony
  • MD Brand Connect
  • MDTV
    • Breaking News
    • Medical News Today
    • Health News Today
    • Latest
    • Journal Club
    • Medico Legal Update
    • Latest Webinars
    • MD Shorts
    • Health Dialogues
Medical Dialogues
  • Medical News & Guidelines
      • Anesthesiology
      • Cardiology and CTVS
      • Critical Care
      • Dentistry
      • Dermatology
      • Diabetes and Endocrinology
      • ENT
      • Gastroenterology
      • Medicine
      • Nephrology
      • Neurology
      • Obstretics-Gynaecology
      • Oncology
      • Ophthalmology
      • Orthopaedics
      • Pediatrics-Neonatology
      • Psychiatry
      • Pulmonology
      • Radiology
      • Surgery
      • Urology
      • Laboratory Medicine
      • Diet
      • Nursing
      • Paramedical
      • Physiotherapy
  • Health news
      • Doctor News
      • Government Policies
      • Hospital & Diagnostics
      • International Health News
      • MCI News
      • Medical Organization News
      • Medico Legal News
      • NBE News
      • NMC News
  • AYUSH
    • Ayurveda
    • Homeopathy
    • Siddha
    • Unani
    • Yoga
  • State News
      • Andaman and Nicobar Islands
      • Andhra Pradesh
      • Arunachal Pradesh
      • Assam
      • Bihar
      • Chandigarh
      • Chattisgarh
      • Dadra and Nagar Haveli
      • Daman and Diu
      • Delhi
      • Goa
      • Gujarat
      • Haryana
      • Himachal Pradesh
      • Jammu & Kashmir
      • Jharkhand
      • Karnataka
      • Kerala
      • Ladakh
      • Lakshadweep
      • Madhya Pradesh
      • Maharashtra
      • Manipur
      • Meghalaya
      • Mizoram
      • Nagaland
      • Odisha
      • Puducherry
      • Punjab
      • Rajasthan
      • Sikkim
      • Tamil Nadu
      • Telangana
      • Tripura
      • Uttar Pradesh
      • Uttrakhand
      • West Bengal
  • Medical Education
      • Ayush Education News
      • Dentistry Education News
      • Medical Admission News
      • Medical Colleges News
      • Medical Courses News
      • Medical Universities News
      • Nursing education News
      • Paramedical Education News
      • Study Aborad
  • Industry
      • Health Investment News
      • Health Startup News
      • Medical Devices News
      • Pharma News
      • Pharmacy Education News
      • Industry Perspective
  • MDTV
      • Health Dialogues MDTV
      • Health News today MDTV
      • Latest Videos MDTV
      • Latest Webinars MDTV
      • MD shorts MDTV
      • Medical News Today MDTV
      • Medico Legal Update MDTV
      • Top Videos MDTV
      • Health Perspectives MDTV
      • Journal Club MDTV
This site is intended for healthcare professionals only
LoginRegister
Medical Dialogues
LoginRegister
  • Home
  • Medical news & Guidelines
    • Anesthesiology
    • Cardiology and CTVS
    • Critical Care
    • Dentistry
    • Dermatology
    • Diabetes and Endocrinology
    • ENT
    • Gastroenterology
    • Medicine
    • Nephrology
    • Neurology
    • Obstretics-Gynaecology
    • Oncology
    • Ophthalmology
    • Orthopaedics
    • Pediatrics-Neonatology
    • Psychiatry
    • Pulmonology
    • Radiology
    • Surgery
    • Urology
    • Laboratory Medicine
    • Diet
    • Nursing
    • Paramedical
    • Physiotherapy
  • Health news
    • Doctor News
    • Government Policies
    • Hospital & Diagnostics
    • International Health News
    • MCI News
    • Medical Organization News
    • Medico Legal News
    • NBE News
    • NMC News
  • AYUSH
    • Ayurveda
      • Ayurveda Giuidelines
      • Ayurveda News
    • Homeopathy
      • Homeopathy Guidelines
      • Homeopathy News
    • Siddha
      • Siddha Guidelines
      • Siddha News
    • Unani
      • Unani Guidelines
      • Unani News
    • Yoga
      • Yoga Guidelines
      • Yoga News
  • State News
    • Andaman and Nicobar Islands
    • Andhra Pradesh
    • Arunachal Pradesh
    • Assam
    • Bihar
    • Chandigarh
    • Chattisgarh
    • Dadra and Nagar Haveli
    • Daman and Diu
    • Delhi
    • Goa
    • Gujarat
    • Haryana
    • Himachal Pradesh
    • Jammu & Kashmir
    • Jharkhand
    • Karnataka
    • Kerala
    • Ladakh
    • Lakshadweep
    • Madhya Pradesh
    • Maharashtra
    • Manipur
    • Meghalaya
    • Mizoram
    • Nagaland
    • Odisha
    • Puducherry
    • Punjab
    • Rajasthan
    • Sikkim
    • Tamil Nadu
    • Telangana
    • Tripura
    • Uttar Pradesh
    • Uttrakhand
    • West Bengal
  • Medical Education
    • Ayush Education News
    • Dentistry Education News
    • Medical Admission News
    • Medical Colleges News
    • Medical Courses News
    • Medical Universities News
    • Nursing education News
    • Paramedical Education News
    • Study Aborad
  • Industry
    • Health Investment News
    • Health Startup News
    • Medical Devices News
    • Pharma News
      • CDSCO (Central Drugs Standard Control Organisation) News
    • Pharmacy Education News
    • Industry Perspective
  • Home
  • Radiology
  • Radiology News
  • Concurrent carbogen...

Concurrent carbogen and nicotinamide with radiation safe, novel option for bladder cancer: Study

Dr. Shravani DaliWritten by Dr. Shravani Dali Published On 2021-07-15T09:00:51+05:30  |  Updated On 2021-07-15T11:30:04+05:30
Concurrent carbogen and nicotinamide with radiation safe, novel option for bladder cancer: Study

Concurrent carbogen and nicotinamide with radiation therapy is a safe, economical, and novel treatment option for patients with muscle-invasive bladder cancer, specifically for patients with limited options, suggests a study published in the Journal of Medical Imaging and Radiation Oncology. When cells of the bladder start growing abnormally, it can lead to bladder cancer. The onset...

Concurrent carbogen and nicotinamide with radiation therapy is a safe, economical, and novel treatment option for patients with muscle-invasive bladder cancer, specifically for patients with limited options, suggests a study published in the Journal of Medical Imaging and Radiation Oncology.

When cells of the bladder start growing abnormally, it can lead to bladder cancer. The onset of bladder cancer increases with age.

Muscle invasive bladder cancer (MIBC) is a type of advanced cancer that affects the detrusor muscle of the bladder, which is a thick muscle deep in the bladder wall. It can also metastasize to other parts of the body. When the elderly suffer from muscle-invasive bladder cancer, it is often not completely treated.

Bladder preservation trimodality therapy (BPTT) is an adjunct to radical cystectomy in the curative setting. However, the utilization of concurrent carbogen and nicotinamide with radiation therapy as radiosensitizers have shown positive outcomes in the overall survival and local relapse rate in the UK BCON Trial and so it is now a part of the routine procedure for these patients in the UK.

A first of its kind study was conducted by a group of Australian researchers to investigate the possibility of setting up a Concurrent carbogen and nicotinamide (CON) radiation oncology department in their country.

The researchers selected 7 participants with histological locally advanced bladder cancer. They set up circuit systems for carbogen gas delivery in consultation with the anesthetics and respiratory teams, as inspired by the UK BCON trial. TGA exemption was obtained for 98% oxygen, 2% carbon dioxide carbogen gas mixture, and delivery apparatus for each patient.

The development of a Concurrent carbogen and nicotinamide (CON) radiation oncology department took almost 24 months. The trial protocol was based on the equipment availability in Australia and proper transport, storage, and handling of the equipment was guided by local occupational, health, and safety (OHS) regulations. All patients received a full of dose of Concurrent carbogen and nicotinamide (CON).

The findings of the study areas follows:

  • The most common acute bladder and bowel toxicities were increased urinary frequency, urgency, and diarrhea.

The researchers concluded that Concurrent carbogen and nicotinamide (CON) with radiation therapy is a completely safe and affordable treatment modality that provides a novel therapeutic alternative for patients with muscle-invasive bladder cancer, particularly those with limited treatment options.

Reference:

Concurrent carbogen and nicotinamide with radiation therapy in muscle-invasive bladder cancer: A report on feasibility in the Australian setting by Anzela A et. al published in the Journal of Medical Imaging and Radiation Oncology.

https://doi.org/10.1111/1754-9485.13265


journal of medical imaging and radiation oncology bladder cancer muscle-invasive bladder cancer concurrent carbogen and nicotinamide older people UK BCON trial 
Source : journal of medical imaging and radiation oncology
Dr. Shravani Dali
Dr. Shravani Dali

    BDS

    Dr. Shravani Dali has completed her BDS from Pravara institute of medical sciences, loni. Following which she extensively worked in the healthcare sector for 2+ years. She has been actively involved in writing blogs in field of health and wellness. Currently she is pursuing her Masters of public health-health administration from Tata institute of social sciences. She can be contacted at editorial@medicaldialogues.in.

    Show Full Article
    Next Story
    Similar Posts
    NO DATA FOUND

    Editorial

    Journal Club Today

    Health News Today

    © 2022 All Rights Reserved.
    Powered By: Hocalwire
    X
    X
    We use cookies for analytics, advertising and to improve our site. You agree to our use of cookies by continuing to use our site. To know more, see our Cookie Policy and Cookie Settings.Ok