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Contrast-enhanced mammography superior to full-field digital mammography: Study

MD Editorial TeamBy MD Editorial TeamPublished On 2021-11-18T09:00:16+05:30  |  Updated On 2021-11-18T09:00:32+05:30
Contrast-enhanced mammography  superior to full-field digital mammography: Study

Contrast-enhanced mammography is an emerging breast imaging modality introduced in 2011 the diagnostic accuracy of which has been found superior to full-field digital mammography (FFDM), even matching the performance of breast MRI, in some studies.A new study has confirmed the superiority and improved sensitivity and specificity of Contrast-enhanced mammography (CEM) compared to...

Contrast-enhanced mammography is an emerging breast imaging modality introduced in 2011 the diagnostic accuracy of which has been found superior to full-field digital mammography (FFDM), even matching the performance of breast MRI, in some studies.

A new study has confirmed the  superiority and improved sensitivity and specificity of Contrast-enhanced mammography (CEM) compared to full-field digital mammography (FFDM).Neeter and peers conducted this work to assess CEM's diagnostic performance on a system from a different vendor.

The findings of this study has been published in Nature on 15th November, 2021.

Except for individuals with incomplete data or for whom CEM was used as a response monitoring technique, researchers included all patients who received CEM at one institution in 2019. The low-energy pictures were graded by three expert breast radiologists using the BI-RADS classification. Following that, the entire set of CEM tests was scored in the same manner. As a reference standard, histopathological findings or a minimum of one year of follow-up were employed. Diagnostic performance and AUC were determined and compared between low-energy pictures and the whole CEM examination, both separately and in combination, for all readers.

Breast cancer was discovered in 23.0% of the patients (35/152). Overall CEM sensitivity rose from 74.3 to 87.6% when compared to low-energy pictures, and specificity increased from 87.8 to 94.6%. The AUC rose from 0.872 to 0.957.

In summary, as compared to FFDM, CEM done on a Hologic system enhanced both sensitivity and specificity. The reported diagnostic performance is within the 95 percent confidence interval of summary ROC curves from a previously published meta-analysis. As a result, it can be fairly stated that the kind of CEM unit does not appear to be a deciding factor in experiments that use equipment from several suppliers.

Reference:

Neeter, L.M.F.H., Raat, H.P.J., Meens-Koreman, S.D. et al. The diagnostic value of contrast-enhanced 2D mammography in everyday clinical use. Sci Rep 11, 22224 (2021). https://doi.org/10.1038/s41598-021-01622-7

Nature journal breast screening contrast-enhanced mammography 
Source : Nature
MD Editorial Team
MD Editorial Team

    Medical Dialogues consists of a team of passionate medical/scientific writers, led by doctors and healthcare researchers. Our team efforts to bring you updated and timely news about the important happenings of the medical and healthcare sector. Our editorial team can be reached at editorial@medicaldialogues.in.

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