Chemical sphincterotomy with calcium channel blockers effectively relieves pain after haemorrhoidectomy

Written By : Dr. Shravani Dali |Medically Reviewed By : Dr. Kamal Kant Kohli Published On 2023-09-26T10:00:59+05:30 | Updated On 26 Sept 2023 12:16 PM IST

Haemorrhoid is one of the most common anal diseases in the world, and it is estimated that the lifetime risk of developing haemorrhoids in the general population may be as high as 75%. Surgical treatment remains the primary modality indicated for high-grade haemorrhoids.

Chemical sphincterotomy with calcium channel blockers effectively relieves pain after haemorrhoidectomy finds a new study.

The study has been published in the BMC Surgery.

This study aims to evaluate the pain relief function of chemical sphincterotomy in patients undergoing haemorrhoid surgery and compare, through a meta-analysis, the different drugs used to treat this condition.

Researchers conducted a search in databases including PubMed, EMBASE and Web of Science. The methodological quality was evaluated using the Revised Cochrane risk-of-bias tool for randomized trials (ROB2). The pain score was assessed using a visual analogue scale (VAS) on day 1, day 2, and day 7, and a meta-analysis was conducted based on the use of random effects models. In addition, the subgroup analysis was evaluated based on the kind of experimental drugs. Heterogeneity and publication bias were assessed.

Results

Fourteen studies with a total of 681 patients were included in this meta-analysis, and all studies were randomized controlled trials RCTs. Chemical sphincterotomy showed better pain relief function than placebo on day 1 (SMD: 1.16, 95% CI 0.52 to 1.80), day 2 (SMD: 2.12, 95% CI 1.37 to 2.87) and day 7 (SMD: 1.97, 95% CI 1.17 to 2.77) after surgery. In the subgroup meta-analysis, we found that different drugs for chemical sphincterotomy provided different pain relief.

Chemical sphincterotomy effectively relieves pain after haemorrhoidectomy, and calcium channel blockers have the best effect.

Reference:

Cheng, Y., Mao, M., Shang, Y. et al. Chemical sphincterotomy in posthemorrhoidectomy pain relief: a meta-analysis. BMC Surg 23, 113 (2023). https://doi.org/10.1186/s12893-023-02025-3

Keywords:

Chemical, sphincterotomy, calcium, channel, blockers, effectively, relieves, pain, haemorrhoidectomy, BMC Surgery, Cheng, Y., Mao, M., Shang, Y.

BMC SurgeryChemicalsphincterotomycalciumchannelblockerseffectivelyrelievespainhaemorrhoidectomy

Source : BMC Surgery

Dr. Shravani Dali

Dr. Shravani Dali has completed her BDS from Pravara institute of medical sciences, loni. Following which she extensively worked in the healthcare sector for 2+ years. She has been actively involved in writing blogs in field of health and wellness. Currently she is pursuing her Masters of public health-health administration from Tata institute of social sciences. She can be contacted at editorial@medicaldialogues.in.

Dr. Kamal Kant Kohli

Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751