Combined Treatment Method may Improve Survival in Anaplastic Thyroid Cancer Patients with Metastasis: Study

Written By : Jacinthlyn Sylvia |Medically Reviewed By : Dr. Kamal Kant Kohli Published On 2024-03-12T03:00:37+05:30 | Updated On 12 March 2024 3:00 AM IST

Anaplastic thyroid cancer (ATC) is a rare and aggressive malignancy which poses significant challenges in treatment and prognosis, specially in the cases with distant metastasis (DM). However, a recent study by Hongen Guo and team indicate that a combination of treatment strategies could enhance the survival rates for patients with this disease. The key findings of this study were published in the recent edition of BMC Surgery.

The study was based on a retrospective analysis of data from the Surveillance, Epidemiology and End Results (SEER) database that focused on anaplastic thyroid cancer patients with distant metastasis at the time of diagnosis. The results from the analysis included a total of 315 anaplastic thyroid cancer patients with distant metastasis and highlighted the key factors influencing survival. Surgical intervention targeting the primary tumor, along with radiotherapy, chemotherapy and the presence of lung metastasis was found to be the significant determinants of prognosis.

The patients who underwent a combination of treatment modalities like the surgery paired with chemotherapy or surgery combined with chemoradiation, expressed markedly improved survival outcomes when compared to the individuals who received only a single form of therapy.

These findings underscore the potential benefits of adopting a multifaceted approach to treating anaplastic thyroid cancer, particularly in cases where the distant metastasis is present. While the results offer promising insights into enhancing treatment efficacy, the outcomes emphasized the need for larger sample cohorts to validate these findings comprehensively.

The outcomes of this research signifies a major step forward in the fight against anaplastic thyroid cancer that offers hope for enhanced treatment strategies and improved survival rates for patients with this rare and aggressive malignancy.

Reference:

Guo, H., & Lin, H. (2024). The value of multimodal treatment in anaplastic thyroid cancer patients with distant metastasis. In BMC Surgery (Vol. 24, Issue 1). Springer Science and Business Media LLC. https://doi.org/10.1186/s12893-024-02375-6

BMC SurgeyAnaplastic thyroid cancerDistant metastasis

Source : BMC Surgery

Jacinthlyn Sylvia

Neuroscience Masters graduate

Jacinthlyn Sylvia, a Neuroscience Master's graduate from Chennai has worked extensively in deciphering the neurobiology of cognition and motor control in aging. She also has spread-out exposure to Neurosurgery from her Bachelor’s. She is currently involved in active Neuro-Oncology research. She is an upcoming neuroscientist with a fiery passion for writing. Her news cover at Medical Dialogues feature recent discoveries and updates from the healthcare and biomedical research fields. She can be reached at editorial@medicaldialogues.in

Dr. Kamal Kant Kohli

Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751