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  • Intraoperative PRBC...

Intraoperative PRBC transfusion may increase pulmonary complications and ICU readmissions after isolated CABG surgery

Written By : Dr. Shravani Dali |Medically Reviewed By : Dr. Kamal Kant Kohli Published On 2024-01-21T21:30:27+05:30  |  Updated On 21 Jan 2024 9:30 PM IST
Intraoperative PRBC transfusion may increase pulmonary complications and ICU readmissions after isolated CABG surgery
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Intraoperative packed red blood cell transfusion may increase pulmonary complications and ICU readmissions after isolated coronary artery bypass graft surgery suggests a new study published in the Annals of Thoracic Surgery.

Intraoperative packed red blood cell (PRBC) transfusion during cardiac surgery is associated with increased postoperative morbidity and mortality; however, data regarding the association between packed red blood cell transfusion and postoperative pulmonary complications (PPCs) is somewhat conflicting. Using the Society of Thoracic Surgeons Adult Cardiac Surgery Database, we sought to determine whether intraoperative packed red blood cell transfusion was associated with postoperative pulmonary complications as well as longer intensive care unit (ICU) stays after isolated coronary artery bypass grafting (CABG) surgery. A registry-based cohort study was performed on 751,893 patients with isolated coronary artery bypass grafting between January 1, 2015, to December 31, 2019. Using propensity-score–weighted regression analysis, they analyzed the effect of intraoperative packed red blood cells on the incidence of postoperative pulmonary complications (hospital-acquired pneumonia [HAP], mechanical ventilation >24 hours or reintubation), ICU length of stay, and ICU readmission. Results: Transfusion of 1, 2, 3 and ³4 units of packed red blood cells was associated with increased odds for hospital-acquired pneumonia, reintubation, prolonged ventilation, initial ICU length of stay, and readmission to ICU. Intraoperative packed red blood cell transfusion was associated with increased incidence of postoperative pulmonary complications, prolonged ICU stay, and ICU readmissions after isolated coronary artery bypass grafting surgery.


Reference:

Jacob Raphael, Alice Chae, Xiaoke Feng, Matthew S. Shotwell, Michael A. Mazzeffi, Bruce A. Bollen, Douglas Pfeil, Eric Feduska, Ashish S. Shah, Miklos D. Kertai,

Red Blood Cell Transfusion and Pulmonary Complications: STS Adult Cardiac Surgery Database Analysis. The Annals of Thoracic Surgery, 2024, ISSN 0003-4975. https://doi.org/10.1016/j.athoracsur.2023.12.012.

(https://www.sciencedirect.com/science/article/pii/S0003497524000055)

Keywords:

Intraoperative PRBC transfusion, pulmonary complications CABG,I CU readmissions, CABG surgery, The Annals of Thoracic Surgery, Society of Thoracic Surgeons’ Adult Cardiac Surgery Database; Red blood cell transfusion; Coronary artery bypass grafting surgery; Hospital acquired pneumonia; Length of stay, Jacob Raphael, Alice Chae, Xiaoke Feng, Matthew S. Shotwell, Michael A. Mazzeffi, Bruce A. Bollen, Douglas Pfeil, Eric Feduska, Ashish S. Shah, Miklos D. Kertai








IntraoperativePRBCtransfusionincreasepulmonarycomplicationsICUreadmissionsisolatedCABG surgeryThe Annals of Thoracic Surgery
Source : The Annals of Thoracic Surgery
Dr. Shravani Dali
Dr. Shravani Dali

    Dr. Shravani Dali has completed her BDS from Pravara institute of medical sciences, loni. Following which she extensively worked in the healthcare sector for 2+ years. She has been actively involved in writing blogs in field of health and wellness. Currently she is pursuing her Masters of public health-health administration from Tata institute of social sciences. She can be contacted at editorial@medicaldialogues.in.

    Dr. Kamal Kant Kohli
    Dr. Kamal Kant Kohli

    Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751

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