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  • Is robot-assisted...

Is robot-assisted radical cystectomy better for patient recovery than open surgery?

Medical Dialogues Editorial TeamWritten by Medical Dialogues Editorial Team Published On 2022-03-02T09:00:20+05:30  |  Updated On 2 March 2022 3:30 AM GMT
Is robot-assisted radical cystectomy better for patient recovery than open surgery?
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USA: In a new study conducted by Vivek Venkatramani and team, it was found that after radical cystectomy, patients take 3 to 6 months to return to baseline levels, regardless of surgical method. The findings of this study were published in the Journal of American Medical Association.After radical cystectomy, no data on time to recovery of patient-reported and performance-related markers...

USA: In a new study conducted by Vivek Venkatramani and team, it was found that after radical cystectomy, patients take 3 to 6 months to return to baseline levels, regardless of surgical method. The findings of this study were published in the Journal of American Medical Association.

After radical cystectomy, no data on time to recovery of patient-reported and performance-related markers of functional independence available (open or robotic). As a result, the goal of this study was to see if functional independence could be restored following radical cystectomy and if robot-assisted radical cystectomy (RARC) has any advantages over open procedures.

The RAZOR (Randomized Open vs Robotic Cystectomy) experiment provided the data for this secondary analysis. RAZOR was a phase 3 multicenter noninferiority study that ran from July 1, 2011, to November 18, 2014, at 15 academic medical institutions across the United States, with a median follow-up of two years. The per-protocol population (n = 302) was among the participants.

From February 1, 2017, through May 1, 2021, data was evaluated. The subjects had robotic-assisted radical cystectomy (RARC) or open radical cystectomy (ORC). The measures of independence were patient-reported (activities of daily living [ADL] and independent ADL [iADL]) and performance-related (handgrip strength [HGS] and Timed Up & Go walking test [TUGWT]). Postoperative recovery Patterns for the entire cohort were studied, as well as comparisons between RARC and ORC. Exploratory analyses were conducted to evaluate measures of independence among diversion types and to see if baseline deficits were linked to 90-day complications or 1-year mortality.

The key findings are as follow:

1. 150 of the 302 patients in the study received RARC, while 152 underwent ORC.

2. Both groups had identical baseline characteristics. ADL, iADL, and TUGWT returned to baseline in the whole sample after three months, but HGS took six months.

3. At any point in time, there was no difference in ADL, iADL, TUGWT, or HGS scores between RARC and ORC. RARC took one month to restore activities of daily life, but ORC took three months to recover.

4. After RARC, handgrip strength returned in 3 months vs. 6 months after ORC. At 3 months, 32 of 90 patients (35.6%) in the RARC group demonstrated recovery in HGS vs 32 of 88 (36.4 percent) in the ORC group, suggesting that the major research hypothesis was rejected.

5. Patients who had a continent urine diversion recovered faster than those who had a noncontinent urinary diversion, with no differences in other parameters. There was no link between baseline deficits in any measure and 90-day complications or 1-year mortality.

In conclusion, these data will be extremely useful in patient counseling and planning. When compared to ORC, handgrip strength and ADL returned to baseline sooner following RARC; however, there was no difference in the percentage of patients who recovered. Further study is needed to assess the clinical significance of these findings.

Reference:

Venkatramani V, Reis IM, Gonzalgo ML, et al. Comparison of Robot-Assisted and Open Radical Cystectomy in Recovery of Patient-Reported and Performance-Related Measures of Independence: A Secondary Analysis of a Randomized Clinical Trial. JAMA Netw Open. 2022;5(2):e2148329. doi:10.1001/jamanetworkopen.2021.48329

JAMA Network OpenRadical cystectomyRecoveryrobotic surgery
Source : JAMA Network Open
Medical Dialogues Editorial Team
Medical Dialogues Editorial Team

    Medical Dialogues consists of a team of passionate medical/scientific writers, led by doctors and healthcare researchers. Our team efforts to bring you updated and timely news about the important happenings of the medical and healthcare sector. Our editorial team can be reached at editorial@medicaldialogues.in.

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