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  • Post-silicone oil...

Post-silicone oil filling Ocular hypertension may change anterior segment anatomy and aqueous humor flow dynamics: Study

Written By : Dr. Shravani Dali |Medically Reviewed By : Dr. Kamal Kant Kohli Published On 2025-01-12T21:15:17+05:30  |  Updated On 13 Jan 2025 11:38 AM IST
Post-silicone oil filling Ocular hypertension may change anterior segment anatomy and aqueous humor flow dynamics: Study
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Post-silicone oil filling Ocular hypertension tied to changes in anterior segment anatomy and aqueous humor flow dynamics suggests a study published in the BMC Surgery.

This study aims to examine the correlation between specific clinical parameters, such as axial eye length, and the onset of ocular hypertension “OH” following the use of silicone oil filling in patients with high myopia. In this retrospective analysis, we reviewed 214 eyes from 432 patients diagnosed with severe myopia, all of whom underwent vitrectomy and were treated with silicone oil filling.

The study aimed to document the incidence and timing of postoperative ocular hypertension “OH” while assessing various factors, including demographic details, medical history, additional surgical interventions, and findings from supplementary examinations (such as axial length, silicone oil emulsification, and anterior chamber penetration). Binary logistic regression was employed as the primary statistical method to identify significant predictors and their relationship with “OH”. This approach allowed for a comprehensive analysis of the impact of the duration of silicone oil presence in the eye on “OH” occurrence, providing a detailed understanding of the factors influencing post-surgical outcomes.

Result : The study revealed a statistically significant increase in postoperative axial length (29.21 ± 0.85 mm) compared to the preoperative length (28.31 ± 0.82 mm), corresponding to an incidence rate of 37.38% (80 cases) for “OH”. Logistic regression analysis identified the following variables as significantly associated with an increased risk of “OH” post-silicone oil filling: scleral buckling, aphakic status, silicone oil emulsification, and silicone oil penetration into the anterior chamber.

The odds ratios (OR) for these variables were 1.397, 0.672, 1.859, and 1.364, respectively, indicating their predictive value for “OH” risk. The development of “OH” post-silicone oil filling is strongly correlated with changes in the anterior segment anatomy and the dynamics of aqueous humor flow, particularly in eyes without the natural lens. Recognizing these risk factors highlights the importance of thorough preoperative evaluation and individualized postoperative care to reduce the incidence of OH in patients with high myopia, thereby improving surgical outcomes.

Reference:

Lin, X., Feng, S., Chen, C. et al. Ocular hypertension after silicone oil filling surgery for high myopia: a case-control study. BMC Surg 25, 7 (2025). https://doi.org/10.1186/s12893-024-02704-9

Post-siliconeoilfillingOcularhypertensiontiedchangesanteriorsegmentanatomyaqueoushumorflowdynamicsstudy
Source : BMC Surgery
Dr. Shravani Dali
Dr. Shravani Dali

    Dr. Shravani Dali has completed her BDS from Pravara institute of medical sciences, loni. Following which she extensively worked in the healthcare sector for 2+ years. She has been actively involved in writing blogs in field of health and wellness. Currently she is pursuing her Masters of public health-health administration from Tata institute of social sciences. She can be contacted at editorial@medicaldialogues.in.

    Dr. Kamal Kant Kohli
    Dr. Kamal Kant Kohli

    Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751

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