ESRD patients undergoing PCI have considerably higher length of hospital stay and mortality

New research has revealed that End stage renal disease patients undergoing percutaneous coronary intervention have considerably higher In-hospital outcomes like mortality, cost, and length of stay than those not having the end-stage renal disease. The study results were published in the journal Cardiovascular Revascularization Medicine. 

 When the kidneys can no longer carry out their normal function, a person has end-stage renal disease and needs renal replacement treatment or a kidney transplant. The major cause of mortality for those with end-stage renal disease (ESRD) is cardiovascular disease due to increased coronary plaque and calcifications leading to a hyper-inflammatory state. Previous literature has shown that ESRD patients undergoing percutaneous coronary intervention (PCI) have an increase in in-hospital mortality and prolonged hospitalization, among other complications when compared with non-ESRD patients undergoing the same procedure. Hence researchers conducted a study to evaluate the in-hospital mortality after PCI in the setting of Acute Coronary Syndrome (ACS) using the National Inpatient Database (NIS) between the years 2016–2019 in ESRD patients. 

Patients who had PCI between 2016 and 2019 were identified using the national inpatient sample (NIS). Patients with ESRD receiving renal replacement therapy (RRT) were then put into separate groups. In-hospital mortality was evaluated using logistic regression models as the primary outcome, while hospitalization costs and duration of stay were evaluated using linear regression models as the secondary outcomes.